KEY FACTS
Terminology
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Failure of closure of lower abdominal wall resulting in exposed bladder
Imaging
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Inability to demonstrate fluid-filled bladder
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Soft tissue mass/nodular contour of lower anterior abdominal wall due to exposed posterior bladder wall
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Normal fluid
Top Differential Diagnoses
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Absent bladder
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Renal anomalies or other conditions with low/absent urine production are associated with oligo/anhydramnios
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If associated with oligohydramnios in monochorionic twin, may indicate twin-twin transfusion syndrome
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Cloacal exstrophy
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Absent fluid-filled bladder, imperforate anus
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Bowel herniation through abdominal wall defect → elephant trunk sign
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Scanning Tips
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Red flag for this diagnosis is normal amniotic fluid without visible bladder
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Obtain midline sagittal image through torso for abdominal wall contour
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Check cord insertion site; inferiorly displaced in bladder exstrophy
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Evaluate for genital anomalies, which are common in both males and females
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Look for anal dimple on axial image of perineum
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Do not confuse cystic pelvic structures with bladder
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Normal bladder fills and empties repeatedly during scan
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Umbilical arteries encompass bladder as they course from internal iliac arteries to umbilicus
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Use 3D surface-rendered ultrasound images to clarify anatomy