KEY FACTS
Terminology
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Benign, fluid-filled nonneoplastic renal lesion not meeting criteria of simple renal cyst, Bosniak classes II, IIF, and III
Imaging
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Round, oval, or irregular-shaped anechoic lesion
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Hemorrhagic cyst: Variable → echogenic fluid, retracting clot, debris level or septations
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Proteinaceous cyst: Low-level echoes with bright reflectors or even layers of echoes
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Infected cyst: Thick wall with scattered internal echoes ± debris-fluid level
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Calcified cyst: Wall or septal calcification ± shadowing
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Neoplastic features: Solid mural or septal nodules, irregular wall, or irregular septal thickening with color flow
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Complex cysts should be evaluated with CEUS, CECT, or CEMR for decision of surgical intervention
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Contrast uptake on CEUS suspicious for malignancy (other than a few bubbles in thin, smooth septa or wall)
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Increased sensitivity for detecting malignancy
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Information analogous to Bosniak classification
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Depending on body habitus and number of cysts, US can fully characterize renal cysts/monitor complex renal cysts
Top Differential Diagnoses
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Renal cell carcinoma (cystic)
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Multilocular cystic nephroma
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Localized cystic disease
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Renal abscess
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Renal metastasis/lymphoma
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Renal lymphoma
Clinical Issues
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20-30% of middle-aged adults; > 50% of patients > 50 years
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Complications: Hydronephrosis, hemorrhage, infection, cyst rupture
Scanning Tips
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Optimize color Doppler settings to detect flow in septa and nodules