Consolidation, Collapse and Cavitation



Consolidation, Collapse and Cavitation





This chapter discusses the radiographic patterns of pulmonary consolidation and illustrates the various pathological processes that can cause it. It also describes the features of partial and complete collapse of the major lobes of the lungs. We are all aware that it may be difficult to decide if there is abnormal parenchymal shadowing on a chest radiograph and most of us will also have missed subtle changes of lobar collapse at some stage in our careers. However, there is a systematic approach to the identification of both consolidation and collapse, and in this chapter I seek to share it. I guarantee that if the system is adopted and practised then eventually ‘pattern recognition’ will take over – in other words, ‘I have seen this pattern of abnormality lots of times before and I know what it is’. However, before any of us reaches this stage of experience, it is vital to be obsessional about following a systematic approach – but then this applies to all aspects of clinical medicine.





Collapse

Consolidated lung may lose volume at any stage in disease progression but the crucial question is whether consolidation is secondary to collapse. The obvious cause of this is major airway obstruction and this has important management implications. Marked loss of volume on the radiograph is likely to indicate pathology causing primary collapse and should be investigated as such.

When the primary process is consolidation, on the other hand, any subsequent loss of volume is not usually dramatic unless the disease is a chronic infective one such as tuberculosis or chronic Klebsiella pneumonia. One of the reasons for emphasizing this point is to question the value of the compromise term ‘consolidation collapse’. To use this description seems scarcely worthwhile because it does not assist in
deciding whether bronchial occlusion is present and therefore fails to materially guide patient management.


Density

When referring to radiographic shadowing, the term ‘density’ refers to the radio-opacity of a lesion and this will be influenced fundamentally by the degree of exposure of the film. With this important qualification and assuming ideal radiographic exposure of the image, I think it is useful to consider three grades of density as follows:



  • low density – small shadows caused by cells or body fluids


  • medium density – larger shadows especially caused by fluids


  • high density – shadows containing radio-opaque atoms either derived from body fluids (iron or calcium) or introduced from the environment (iron, calcium, barium or tin).

Inevitably, these distinctions will be subjective to a certain extent and, in particular, the separation of low- and medium-density shadows can be difficult but the classification is still helpful and I would recommend it to you.


A SYSTEMATIC APPROACH TO CONSOLIDATION (OR ALVEOLAR FILLING)


Ensure that the abnormal shadowing represents an alveolar-filling process

Extensive pulmonary infiltrates of various types can coalesce and mimic ‘alveolar filling’. Examine the nature of the shadowing carefully – is it truly homogeneous or does it appear to be a coalescence of rounded shadows (nodular), streaky shadows (reticular) or a combination of the two (reticulo-nodular)? The intrapulmonary shadowing in Fig. 3.2 is certainly generalized and may appear homogeneous at first
sight but closer inspection reveals that it is made up of myriads of tiny dots in all areas of the lung fields. It almost looks as though someone has scattered the contents of a salt-cellar over the film – this is an example of military tuberculosis.






Figure 3.2 Miliary tuberculosis.


What is the distribution of the abnormal shadowing?

Lobar pneumonia affects lobes or segments uniformly (Figs 3.3 and 3.4). Although pneumonia caused by a variety of infecting agents, including Pneumococcus, can
affect multiple lobes or segments, the radiographic appearance of multiple segmental or subsegmental consolidation should arouse diagnostic suspicion of non-infective aetiology:






Figure 3.3 Pneumococcal pneumonia affecting the right middle lobe. The consolidation has a sharp upper border where it abuts the horizontal fissure. The heart border is lost, indicating that this is anterior shadowing and therefore confirming middle lobe involvement. There is no air bronchogram, which can happen with pneumococcal and other bacterial pneumonias (staphylococcal and Gramnegatives especially) when exudate fills the airways as well as the lung parenchyma.






Figure 3.4 Pneumococcal pneumonia in the right lower lobe. This time the heart border is preserved, the upper boundary is indistinct and the right hemidiaphragm is blurred.



  • If the shadowing is predominantly peripheral, eosinophilic pneumonia should be considered (Fig. 3.5). In the majority of cases, a circulating eosinophilia provides a clue to the diagnosis but this isn’t always present and lung biopsy may be needed to confirm the nature of the eosinophilic infiltrate.


  • Other non-infective but inflammatory conditions cause multisegmental consolidation. Figure 3.6 is an example of cryptogenic organizing pneumonitis, an inflammatory condition with a clinical presentation that commonly mimics pneumonia.


  • Both of these conditions require treatment with corticosteroids, emphasizing the management implications of distinguishing non-infective causes of consolidation.


  • Wegener’s granulomatosis is a vasculitic disease, which characteristically produces multiple areas of consolidation when it affects the lungs. These lesions commonly cavitate (Fig. 3.7).


  • On rare occasions, sarcoidosis causes multisegmental consolidation (Fig. 3.8). In Fig. 3.9 there are nodules as well as patches of consolidation.


  • Malignant infiltrates (haematological, lymphoproliferative and solid tissue tumours) are also in the differential diagnosis of multisegmental consolidation.







Figure 3.5 Eosinophilic pneumonia. The peripheral consolidation in this example is asymmetric with involvement of all areas of the right lung but only the apex on the left.







Figure 3.6 Cryptogenic organizing pneumonitis. Suspicion regarding the original diagnosis of pneumonia arose when no organism was identified and there was a lack of response to antibiotics. The correct diagnosis was made on lung biopsy.






Figure 3.7 Wegener’s granulomatosis. There are patches of consolidation in the right upper and left lower zones and cavitation can be seen in the former.







Figure 3.8 Bilateral multiple segmental consolidation in sarcoidosis.






Figure 3.9 Nodules are present as well as confluent areas of consolidation. The bilateral hilar lymphadenopathy is a clue to the diagnosis of sarcoidosis.


Other recognizable radiographic patterns include:



  • Pulmonary oedema. This has a characteristic perihilar distribution and the epithet, ‘Bat’s wing of death’, though unfortunate, is often appropriate morphologically (Fig. 3.10).


  • Aspiration pneumonia is one cause of bilateral consolidation in the lower zones. Loss of volume may accompany the consolidation as a result of bronchial obstruction from aspirated.


  • Alveolar haemorrhage is commonly perihilar in distribution but this isn’t totally reliable – the major haemorrhage shown in Fig. 3.11 has resulted in extensive
    bilateral consolidation. There is no air-bronchogram within the shadowing because blood is filling the airways as well as the alveoli.






Figure 3.10 Pulmonary oedema – the ‘bat’s-wing’ appearance.






Figure 3.11 Extensive intrapulmonary haemorrhage in a patient with idiopathic pulmonary haemosiderosis.

In contrast:



  • There are no distinguishing radiographic features displayed by the bilateral alveolar filling pattern in the example of pulmonary alveolar proteinosis shown in Fig. 3.12 and the same applies to most cases of Pneumocystis carinii pneumonia (Fig. 3.13) and alveolar cell carcinoma (Fig. 3.14). The consolidation in Fig. 3.15 is as a result of the adult respiratory distress syndrome and, although the multitude of tubes and wires may be a clue as to aetiology, there is nothing diagnostic about the radiograph per se.






Figure 3.12 Pulmonary alveolar proteinosis.






Figure 3.13 Extensive bilateral alveolar-filling pattern in Pneumocystis carinii pneumonia complicating human immunodeficiency virus (HIV) infection.







Figure 3.14 Alveolar cell carcinoma.






Figure 3.15 Adult respiratory distress syndrome. The pulmonary flotation catheter, nasogastric and endotracheal tubes, intercostal chest drain and electrocardiogram wires are a give-away that this film was taken on an intensive care unit.




What is the density of the shadowing?

Sometimes consolidation is of low density, but more commonly it is medium dense, representing as it does alveoli filled with fluid, cells, infective organisms or a mixture of these components. Heavy-density shadowing is not seen except under unusual circumstances, for example if a radiodense foreign body is responsible for bronchial obstruction (see Clinical connections).


Jun 5, 2016 | Posted by in RESPIRATORY IMAGING | Comments Off on Consolidation, Collapse and Cavitation

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