KEY FACTS
Terminology
- •
Chronic internal jugular vein (IJV) thrombosis (> 10 days after acute event) where clot persists within lumen after soft tissue inflammation is gone
- •
JV thrombophlebitis: Acute-subacute thrombosis of IJV with associated adjacent tissue inflammation
Imaging
- •
Acute thrombophlebitic phase
- ○
Loss of fascial planes between IJV & surrounding soft tissues + cellulitis
- ○
Echogenic intraluminal thrombus, distended, noncompressible IJV
- ○
Acute thrombus may be anechoic & difficult to distinguish from flowing blood; lack of compressibility & absent color or flow signal on Doppler may be only clues
- ○
Loss of venous pulsation & respiratory phasicity
- ○
No flow seen within echogenic venous thrombus
- ○
Tumor infiltration of IJV causes tumor thrombus with ↑ vascularity on Doppler US, most commonly from thyroid anaplastic carcinoma or follicular carcinoma
- ○
- •
Chronic phase
- ○
Collateral veins may be detected
- ○
Central liquefaction or heterogeneity of thrombus
- ○
Thrombus tends to be well organized & echogenic
- ○
May be difficult to separate from perivascular echogenic tissues
- ○
Absence of phasicity in jugular or subclavian veins may suggest more central nonocclusive thrombus
- ○
Top Differential Diagnoses
- •
Sluggish or turbulent flow in IJV (pseudothrombosis)
- •
Suppurative lymphadenopathy, neck abscess
- •
SCCa malignant lymphadenopathy
Scanning Tips
- •
Scan neck in neutral flat supine position; if head is elevated, cerebral venous drainage occurs mainly via vertebral vein & IJV will be collapsed
- •
Avoid over-rotation of head to contralateral side, as this may cause neck musculature to compress vein