KEY FACTS
Terminology
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Chronic internal jugular vein (IJV) thrombosis (> 10 days after acute event) where clot persists within lumen after soft tissue inflammation is gone
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JV thrombophlebitis: Acute-subacute thrombosis of IJV with associated adjacent tissue inflammation
Imaging
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Acute thrombophlebitic phase
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Loss of fascial planes between IJV & surrounding soft tissues + cellulitis
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Echogenic intraluminal thrombus, distended, noncompressible IJV
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Acute thrombus may be anechoic & difficult to distinguish from flowing blood; lack of compressibility & absent color or flow signal on Doppler may be only clues
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Loss of venous pulsation & respiratory phasicity
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No flow seen within echogenic venous thrombus
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Tumor infiltration of IJV causes tumor thrombus with ↑ vascularity on Doppler US, most commonly from thyroid anaplastic carcinoma or follicular carcinoma
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Chronic phase
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Collateral veins may be detected
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Central liquefaction or heterogeneity of thrombus
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Thrombus tends to be well organized & echogenic
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May be difficult to separate from perivascular echogenic tissues
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Absence of phasicity in jugular or subclavian veins may suggest more central nonocclusive thrombus
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Top Differential Diagnoses
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Sluggish or turbulent flow in IJV (pseudothrombosis)
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Suppurative lymphadenopathy, neck abscess
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SCCa malignant lymphadenopathy
Scanning Tips
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Scan neck in neutral flat supine position; if head is elevated, cerebral venous drainage occurs mainly via vertebral vein & IJV will be collapsed
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Avoid over-rotation of head to contralateral side, as this may cause neck musculature to compress vein
filled with heterogeneous, laminated intraluminal thrombus
. This patient had known H&N squamous cell carcinoma, and thrombosed IJV could well be mistaken for metastatic node. Note the adjacent round, hypoechoic, metastatic node
, CCA
, and thyroid gland
.
. Note absence of flow signal within venous lumen & thrombus.
, arising from a malignant thyroid mass
and extending into the IJV via the middle thyroid vein
(also filled with thrombus & distended). Note remnant lumen of the vein
and uninvolved CCA
.
& in the middle thyroid vein thrombus
, suggesting these to be tumor thrombi. Note flow signal within remnant lumen of the IJV
and uninvolved CCA
.
with surrounding soft tissue inflammatory changes. Also note edema fluid in retropharyngeal space
.
. Venae vasorum of IJV wall enhances. Note the absence of surrounding soft tissue inflammatory changes.







