Noninvasive Evaluation: Lower Extremity Arteries
Joseph F. Polak
James F. Benenati
Segmental Pressure Measurements of the Lower Extremity: Ankle-Brachial Index and Stress Testing
Indications
1. History of claudication
2. Clinical findings of arterial insufficiency
4. Postoperative surveillance of infrainguinal bypass grafts (traditional)
5. Short- and long-term follow-up of endovascular interventions, including thrombolysis, balloon angioplasty, and endovascular stenting
Contraindications
1. Open wounds
2. Recent surgery
Preprocedure Preparation
None
Procedure
1. Pressure cuffs are positioned around the upper and lower thigh and the upper and lower calf. The segments have been designated high thigh (HT), above-knee (AK), below-knee (BK), and ankle (A). Most commonly, cuffs of 10 to 12 cm in diameter with expandable bladders long enough to encircle the extremity are used (3).
2. Doppler signals are detected in either the dorsalis pedis or the posterior tibial artery.
3. Each blood pressure (BP) cuff is inflated in turn, and the systolic pressure determines when a Doppler signal is detected in the dorsalis pedis or posterior tibial branch.
4. A systolic BP measurement is taken from both arms at the brachial artery. By convention, the higher of the two systolic pressure values is used to calculate the pressure index for both legs. A difference of greater than 10 mm Hg in the systolic pressures should prompt an investigation of the upper extremities.
5. A ratio is constructed between the peak systolic pressure measured during deflation of the ankle cuffs and the systolic brachial pressure: the ankle-brachial index (ABI).
6. Stress testing is essential when evaluating claudication because exams at rest may be near normal.
a. Stress testing is performed with the patient walking on a treadmill with a 12-degree incline, moving at 2 miles per hour. BP cuffs are placed on the ankles. Electrocardiogram (ECG) monitoring is performed during stress.
b. The patient exercises for 5 minutes or until the symptoms are reproduced. Sequential ankle pressures are measured at 30-second intervals for the first
4 minutes and then every minute until the pressure measurement returns to normal or to the pre-exercise level (3).
4 minutes and then every minute until the pressure measurement returns to normal or to the pre-exercise level (3).
Postprocedure Management
None
Results
1. ABI
a. Normal: ABI = 1.0 or slightly greater, but greater than 1.2 indicates disease.
b. Claudication (mild stenosis or occlusion): ABI = 0.8 to 0.9
c. Moderate claudication: 0.5 to 0.8
d. Severe claudication: 0.4 to 0.5
e. Rest pain (severe occlusive disease): ABI <0.4
2. Prognosis for healing skin lesions of toes and feet (1): The probability of healing in diabetic and nondiabetic patients is listed in Table e-66.1.
3. A drop of 15 to 30 mm Hg or greater in peak systolic pressure between the different segments is considered abnormal, indicating a significant lesion located between the two cuffs (4).
4. If the segmental BP at a particular level has a discrepancy of at least 20 mm Hg less than the opposite limb measured at the same level, a “horizontal” pressure gradient is present. This is indicative of a critical lesion proximal to the cuff of the extremity with the lower pressure (4).
5. An HT pressure less than 20 mm Hg above the brachial pressure is considered abnormal. This is consistent with:
a. Stenosis or occlusion of the aorta, iliac artery, or common femoral artery
b. Superficial femoral artery disease combined with stenosis or occlusion of the deep (profunda) femoral artery. The pulse volume recordings (PVRs) should help in the differential diagnosis (see the section on “Pulse Volume Recording”).
c. Significant stenosis of the brachiocephalic vessels.
6. Normal response to exercise is unchanged or there is slight elevation of the pressure measurement. Any decline in pressure is a marker for significant arterial disease. The severity of the disease is indicated by the time it takes for the pressures to return to the pretest level.
a. Single level of disease: 2 to 6 minutes
b. Multiple levels of disease: 6 to 12 minutes
c. Severe occlusive disease: up to 30 minutes or longer
7. Ankle pressures during exercise and rest are used as objective criteria for the clinical categories of chronic limb ischemia (Table e-66.2) (5).