KEY FACTS
Terminology
- •
Definition: Genitourinary tract obstruction (at any level) causing renal parenchymal destruction
Imaging
- •
Progression: Urinary tract dilation (UTD) → ↑ renal echogenicity → small peripheral cortical cysts → large cysts
- ○
Findings are variable depending on stage of progression
- ○
- •
Compare kidney echogenicity with liver echogenicity
- ○
Normal kidney echogenicity ≤ liver echogenicity
- ○
Abnormal kidney echogenicity > liver echogenicity
- ○
Cortical cysts are always abnormal finding
- ○
- •
Variable appearance of UTD
- ○
Depends on level and age of obstruction
- ○
- •
Variable amniotic fluid volume (unilateral vs. bilateral)
- •
Most common causes of obstructive renal dysplasia (ORD)
- ○
Severe ureteropelvic junction obstruction
- ○
Posterior urethral valves in male fetus
- ○
Top Differential Diagnoses
- •
Multicystic dysplastic kidney
- ○
Can look exactly like late ORD
- ○
- •
Non-ORD
- ○
Echogenic kidneys without UTD
- ○
- •
Autosomal recessive polycystic kidney disease
- ○
Large echogenic kidneys is key finding
- ○
Without UTD and without visible cysts
- ○
Scanning Tips
- •
Look carefully for small cortical cysts in kidneys with significant hydronephrosis
- •
Look for unilateral loss of corticomedullary differentiation (CMD) as early finding
- ○
Note that CMD is not always seen in fetus
- ○
- •
Measure contralateral kidney to see evidence for compensatory hypertrophy
- ○
Contralateral kidney compensates for abnormal kidney and is considered “super kidney”
- ○