KEY FACTS
Terminology
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Secondary (metastatic) neoplasms to ovary
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Krukenberg tumor: Subtype of metastatic tumors containing > 10% mucin-filled signet cells in cellular stroma
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High-stage mucinous tumors involving ovary frequently represent metastases from extraovarian primary sites and are often misdiagnosed as primary ovarian mucinous tumors
Imaging
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Bilateral ovarian masses in patients with known primary carcinoma
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Metastases to ovary are usually solid masses
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Often large
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Lobulated masses with smooth external contour
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US
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Solid or cystic and solid
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Solid components demonstrate vascularity on Doppler evaluation
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Typically heterogeneous
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May be complicated by hemorrhage
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CECT
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Solid components often demonstrate heterogeneous enhancement
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Cystic and necrotic areas do not enhance
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MR
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T2WI: Solid components demonstrate heterogeneous signal intensity
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T1WI C+: Solid components show marked heterogeneous enhancement
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PET/CT is modality of choice for tumor staging and shows increased metabolic uptake in ovarian metastases
Top Differential Diagnoses
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Primary ovarian cancer
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Ovarian lymphoma
Scanning Tips
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Look for ascites, which is often seen in the setting of Krukenberg tumor