Ovarian Metastases Including Krukenberg Tumor





KEY FACTS


Terminology





  • Secondary (metastatic) neoplasms to ovary



  • Krukenberg tumor: Subtype of metastatic tumors containing > 10% mucin-filled signet cells in cellular stroma



  • High-stage mucinous tumors involving ovary frequently represent metastases from extraovarian primary sites and are often misdiagnosed as primary ovarian mucinous tumors



Imaging





  • Bilateral ovarian masses in patients with known primary carcinoma



  • Metastases to ovary are usually solid masses



  • Often large



  • Lobulated masses with smooth external contour



  • US




    • Solid or cystic and solid



    • Solid components demonstrate vascularity on Doppler evaluation



    • Typically heterogeneous



    • May be complicated by hemorrhage




  • CECT




    • Solid components often demonstrate heterogeneous enhancement



    • Cystic and necrotic areas do not enhance




  • MR




    • T2WI: Solid components demonstrate heterogeneous signal intensity



    • T1WI C+: Solid components show marked heterogeneous enhancement




  • PET/CT is modality of choice for tumor staging and shows increased metabolic uptake in ovarian metastases



Top Differential Diagnoses





  • Primary ovarian cancer



  • Ovarian lymphoma



Scanning Tips





  • Look for ascites, which is often seen in the setting of Krukenberg tumor







Gross pathology specimen shows ovarian metastasis from gastric cancer (Krukenberg tumor). Bilateral, solid ovarian masses are depicted.








Longitudinal endovaginal US shows a large, solid adnexal mass in a patient with gastric cancer. Note the small foci of calcification , which can rarely be seen in mucinous gastric adenocarcinomas.








Longitudinal color Doppler US shows flow within a solid, large right adnexal mass in a patient with metastatic melanoma to the ovary. Note the free fluid in the cul-de-sac.








Coronal CECT in a 45-year-old woman shows large, bilateral, complex cystic and solid adnexal masses . The patient had a recent history of colon cancer, and these were confirmed metastases at oophorectomy.








Axial CECT shows bilateral ovarian metastases from colon cancer. The uterus is also seen.








Axial CECT shows bilateral ovarian metastases with cystic and solid components. The uterus is also seen.








Axial CECT shows bilateral ovarian metastases from gastric cancer (Krukenberg tumor). Bilateral, heterogeneously enhancing, solid adnexal masses are seen.








Axial CECT shows bilateral, heterogeneously enhancing ovarian metastases . The uterus is also seen. There is a small amount of pelvic ascites .





Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Ovarian Metastases Including Krukenberg Tumor

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