Peritoneal Carcinomatosis





KEY FACTS


Terminology





  • Peritoneal spread of tumor from epithelial malignancy resulting in peritoneal thickening, omental infiltration, serosal implants, and ascites



Imaging





  • Implants develop where peritoneal fluid collects: Dome of liver, omentum, paracolic gutters, and pelvic recesses



  • Peritoneal masses may be solid, cystic, or mixed, depending on primary neoplasm



  • Hypoechoic rind-like thickening of peritoneum or discrete irregular nodular masses along peritoneum



  • Omental involvement may be nodular or diffuse, producing an omental cake




    • Thickened and hypoechoic or heterogeneous with preserved islands of echogenic fat




  • Ascites: Complex with septations or internal echoes (jiggle with transducer pressure)



  • Thickening of mesenteric leaves due to desmoplastic reaction; typically mesenteric side of terminal ileum



  • Color Doppler flow in solid omental/peritoneal deposits



Top Differential Diagnoses





  • Pseudomyxoma peritonei



  • Peritoneal mesothelioma



  • Peritoneal tuberculosis



  • Peritoneal sarcomatosis



  • Peritoneal lymphomatosis



Clinical Issues





  • Present with abdominal distension and pain, weight loss, malaise, fever



  • May have elevated tumor markers such as CA125 or CEA



  • Prognosis variable depending on primary tumor but generally poor prognosis



Scanning Tips





  • Use linear transducers to evaluate anterior peritoneum







Longitudinal ultrasound of the midline anterior abdominal wall in a patient with metastatic pancreatic neuroendocrine carcinoma shows 2 peritoneal soft tissue implants growing through the anterior abdominal wall with adjacent ascites and bowel .








Longitudinal ultrasound of the right upper quadrant inferior to the liver shows ascites and a thick lobular omental cake from pancreatic carcinomatosis.








Transverse color Doppler ultrasound of the midline anterior abdominal wall shows ovarian carcinomatosis and an omental cake . Color flow is present within the omentum. A small amount of ascites is noted.








Transverse ultrasound of the right upper quadrant shows complex septated ascites anterior to the liver , representing mucinous carcinomatosis from appendiceal carcinoma.








Transverse ultrasound shows an omental mass being biopsied using a needle guide .








Longitudinal ultrasound shows the periumbilical region in a patient with diffuse intraperitoneal tumor , growing out through the umbilicus . Biopsy of the umbilical mass showed metastatic adrenal cortical carcinoma.





Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Peritoneal Carcinomatosis

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