KEY FACTS
Imaging
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Exclusively in male fetuses
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Bladder often grossly dilated, filling entire abdomen and increasing abdominal circumference
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Distended bladder “funnels” into urethra
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Keyhole sign from dilated posterior urethra
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Small, bell-shaped chest
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Hydronephrosis/hydroureter
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Rupture → urinoma or urinary ascites
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Oligohydramnios or anhydramnios in severe cases
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Kidneys may show signs of obstructive renal dysplasia
Top Differential Diagnoses
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Cloacal malformation seen exclusively in females
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Dilated, fluid-filled vagina can mimic bladder
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Prune-belly syndrome
Clinical Issues
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Most common cause of fetal lower urinary tract obstruction
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Variable degree of fetal renal damage, directly affects long-term outcomes and survival (overall mortality: 25-50%)
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May tap fetal bladder and assess urine electrolytes
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Intervention (e.g., vesicoamniotic shunt) may be considered in cases with good prognostic markers
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Scanning Tips
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If bladder appears large, check several times during exam to see if it decompresses
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Likely normal if otherwise normal urinary tract and normal amniotic fluid
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Determine sex
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May be difficult in setting of oligohydramnios
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If female, what appears to be a dilated bladder may actually be vagina
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Obtain focused images of bladder base to evaluate for dilation of posterior urethra (keyhole)
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Evaluate kidneys for signs of renal parenchymal damage
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Increased echogenicity, small cortical cysts, atrophy
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