Anatomic scan (MPRAGE [T1] &/or T2): 3-6 minutes per scan

Field map (for optional distortion correction): 3-5 minutes

Diffusion tensor imaging: 4-10 minutes, depending on number of directions, averages used

BOLD task sequences: 2-8 tasks of 4-6 minutes each

BOLD resting state: 5-50 minutes of imaging, may be broken into blocks

Total scan time as clinically required and tolerated by patient: Usually 30-60 minutes

Use T2 or 3D FLAIR anatomic image for tumors best seen on fluid-sensitive sequences

If contrast is desired, acquire BOLD images first, then MPRAGE or stereotactic 3D T1 sequence post contrast

Patients often have difficulty holding still for longer sequences; target 4-7 minutes for each sequence

Repeat key task sequences for improved signal to noise ratio

Task runs can be used for resting-state analyses, but there will be systematic changes in functional connectivity if comparing to normative data acquired during resting state

Use same slice locations and thickness for field map and BOLD acquisitions

Parallel imaging is helpful for most pulse sequences if available, particularly at 3T

Although some BOLD tasks activate only limited brain slices, whole-brain coverage is advised as coregistration to anatomic image is problematic for partial-brain acquisitions