Transposition of the Great Arteries (TGA)





KEY FACTS


Terminology





  • Ventriculoarterial discordance (arteries are switched)




    • Aorta arises from right ventricle (RV), pulmonary artery (PA) arises from left ventricle (LV)




Imaging





  • 4-chamber view is normal in TGA: Outflow tract assessment is key to making diagnosis




    • Outflow tracts parallel as they exit heart



    • PA arises from LV, bifurcates early




      • Left ventricular outflow tract obstruction in 25%




    • Aorta arises from RV, gives rise to arch/head and neck vessels




      • Coarctation of aorta in 5%





  • Ventricular septal defect (VSD) in 40-45%



Top Differential Diagnoses





  • Double-outlet RV




    • Only other diagnosis with parallel outflow tracts




Clinical Issues





  • Postnatally TGA is lethal without treatment




    • Must detect on prenatal scan for appropriate planning




Scanning Tips





  • Never assume vessel from LV is aorta: Verify by showing head and neck branches



  • Never assume vessel from RV is PA: Verify by showing early division into branch PAs



  • If parallel outflow tracts are seen




    • Identify LV, RV, look for VSD



    • Differentiate aorta from PA



    • Look for outflow tract obstruction




  • If only 2 vessels visible on 3-vessel view




    • Superior vena cava (SVC) + normal-sized vessel → transposition of great arteries




      • Both great arteries are present but aligned abnormally so not visible on same axial plane




    • SVC + large vessel → truncus








Four-chamber view in a fetus with TGA looks normal. The RV is anterior , the LV posterior , and the ventricular septal defect (VSD) is not visible. Without real-time video clips and outflow tract assessment, significant congenital heart disease will be missed.

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Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Transposition of the Great Arteries (TGA)

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