KEY FACTS
Terminology
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Ventriculoarterial discordance (arteries are switched)
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Aorta arises from right ventricle (RV), pulmonary artery (PA) arises from left ventricle (LV)
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Imaging
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4-chamber view is normal in TGA: Outflow tract assessment is key to making diagnosis
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Outflow tracts parallel as they exit heart
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PA arises from LV, bifurcates early
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Left ventricular outflow tract obstruction in 25%
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Aorta arises from RV, gives rise to arch/head and neck vessels
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Coarctation of aorta in 5%
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Ventricular septal defect (VSD) in 40-45%
Top Differential Diagnoses
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Double-outlet RV
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Only other diagnosis with parallel outflow tracts
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Clinical Issues
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Postnatally TGA is lethal without treatment
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Must detect on prenatal scan for appropriate planning
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Scanning Tips
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Never assume vessel from LV is aorta: Verify by showing head and neck branches
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Never assume vessel from RV is PA: Verify by showing early division into branch PAs
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If parallel outflow tracts are seen
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Identify LV, RV, look for VSD
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Differentiate aorta from PA
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Look for outflow tract obstruction
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If only 2 vessels visible on 3-vessel view
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Superior vena cava (SVC) + normal-sized vessel → transposition of great arteries
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Both great arteries are present but aligned abnormally so not visible on same axial plane
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SVC + large vessel → truncus
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