GROSS ANATOMY
Overview
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Body (corpus) : Upper 2/3 of uterus
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Fundus: Superior to ostia of fallopian tubes
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Cervix : Lower 1/3 of uterus
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Isthmus: Junction of body and cervix
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Parametrium : Tissue immediately surrounding uterus
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Myometrium : Smooth muscle forming bulk of uterus
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Endometrium : Composed of 2 layers
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Stratum basalis attached to myometrium, does not change
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Stratum functionalis: Thicker, varies with cycle
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Uterus is extraperitoneal in midline of true pelvis
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Uterine position
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Flexion is axis of uterine body relative to cervix
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Version is axis of cervix relative to vagina
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Anteversion ± anteflexion is most common
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Peritoneum extends over bladder dome anteriorly and rectum posteriorly
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Vesicouterine pouch (anterior cul-de-sac) : Anterior recess between uterus and bladder
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Rectouterine pouch of Douglas (posterior cul-de-sac) : Posterior recess between vaginal fornix and rectum; most dependent portion of peritoneum in female pelvis
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Supporting ligaments
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Broad ligaments: Extend laterally to pelvic wall and form supporting mesentery for uterus
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Round ligaments: Arise from uterine cornu and course through inguinal canal to insert on labia majora
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Uterosacral ligaments (posteriorly), cardinal ligaments (laterally), and vesicouterine ligaments (anteriorly) form from connective tissue thickening by cervix
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Fallopian tubes connect uterus to peritoneal cavity
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4 segments: Interstitial (portion going through myometrium at cornua), isthmus, ampulla, infundibulum
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Arteries : Dual blood supply
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Uterine artery (UA) arises from internal iliac artery, anastomoses with ovarian artery
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UA crosses over the ureter and enters uterus just above cervix
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Arcuate arteries arise from UAs; seen in outer 1/3 of myometrium → radial arteries → spiral arteries (endometrium)
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Uterine Variations With Age
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Neonatal: Prominent size secondary to effects of residual maternal hormone stimulation
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Infantile: Corpus < cervix (1:2)
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Prepubertal: Corpus = cervix (1:1)
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Reproductive: Corpus > cervix (2:1)
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7.5-9.0 cm (length); 4.5-6.0 cm (width); 2.5-4.0 cm (thickness)
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Postmenopausal: Overall reduction in size, similar to prepubertal uterus
IMAGING ANATOMY
Myometrium
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Inner layer (junctional zone): Thin and hypoechoic, < 12 mm
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Middle layer: Thick, homogeneously echogenic
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Outer layer: Thin, hypoechoic layer peripheral to arcuate vessels
Endometrium
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Proliferative phase (follicular phase of ovary)
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Cessation of menses to ovulation (up to day 14)
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Estrogen induces proliferation of functionalis layer
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Early: Thin, single echogenic line
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Progressive hypoechoic thickening (4-8 mm), classic trilaminar appearance
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Secretoryphase (luteal phase of ovary)
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Ovulation to beginning of menstrual phase (days 14-28)
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Increased echogenicity and progressive thickening up to 16 mm
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Menstrual phase
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Early: Cystic areas within echogenic endometrium indicating endometrial breakdown
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Progressive heterogeneity with mixed cystic (blood) and hyperechoic (clot or sloughed endometrium) regions
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Imaging Recommendations
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Start with transabdominal exam, typically using curved low-frequency transducer
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Gives “lay of the land”
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Large lesions, particularly exophytic fibroids, may be much better seen transabdominally
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Bladder should be partially full to push small bowel away and create an acoustic window
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With rare exception (young virginal females), transvaginal exam should be performed for more detail
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Sweep completely through uterus in both longitudinal and transverse planes
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Angle probe posteriorly to evaluate cul-de-sac
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Most dependent portion so free fluid and other peritoneal pathology implants in this area
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Gently push on probe to show uterus slides easily over bowel ( sliding sign )
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Adhesions (e.g., endometriosis) causes organs to be fixed
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Measure uterus in all 3 dimensions and document all myometrial lesions
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Entire length of endometrium needs to be evaluated in sagittal (longitudinal) plane
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Measure thickest point perpendicular to endometrial stripe
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If fluid is in the canal, measure each side separately and add measurements together
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Color and pulsed-wave Doppler should be performed on any suspicious lesions
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3D ultrasound additive in many cases, particularly müllerian duct (duplication) anomalies and intrauterine device evaluation
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3D volume data sets are acquired and can be manipulated to show optimal projection
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May also slice through data set creating individual images similar to CT
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Perform at beginning of transvaginal scan before bladder starts to refill
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Sonohysterography, with infusion of saline into endometrial cavity, may be used to evaluate endometrial pathology
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Polyps vs. submucosal fibroid, hyperplasia, carcinoma
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UTERUS