FINDINGS Figure 110-1. Coronal T2WI through the midbrain. There is a thin “horseshoe” brain mantle (vertical arrows) surrounding an enlarged single ventricle (star). There is a band of hyperintense white matter (WM) underneath the smooth cortical gray matter (GM) without significant sulcation. The thalami are fused (transverse arrows). Figure 110-2. Axial T2WI through the thalami. There is fusion of the thalami (star) and the frontal lobes. There is an attempt at formation of anterior interhemispheric fissure (vertical arrow). Figure 110-3. Axial T1WI through the lateral ventricles. This again confirms the univentricle without septum pellucidum or corpus callosum. There is a wide posterior notch possibly interhemispheric fissure (arrow).
DIFFERENTIAL DIAGNOSIS Hydrocephalus, HPE, lissencephaly, hydranencephaly.
DIAGNOSIS HPE with lissencephaly.
DISCUSSION