CASE 158 A 44-year-old woman with breast cancer who has been receiving chemotherapy through an indwelling right-sided central line has recently had swelling of the right upper extremity (Figs. 158.1, 158.2, and 158.3). • To block thyroid uptake, potassium perchlorate (400 mg) is administered by mouth 15 minutes before technetium 99mTc-pertechnetate. • Indwelling catheters with subcutaneous chambers (such as those of the Port-A-Cath) need to be accessed with sterile technique. • With the patient lying supine, butterfly needles attached to a three-way stopcock are connected to the accessed central line ports and also placed into a vein in each upper extremity. • Connected to the stopcocks are 1-mL syringes containing approximately 5 mCi of 99mTc-pertechne-tate in a volume of 0.1 to 0.3 mL and 10-mL syringes containing 10 mL of normal saline. • Gamma camera with a large field of view • Low-energy, parallel-hole, high-resolution collimator • Energy window 20% centered at 140 keV • The camera is positioned over the anterior chest and shoulders with the heart in the center of the field of view. • The tracer is administered as a bolus injection followed by the infusion of 10-mL flushes of normal saline in rapid sequence: first into the upper extremity ipsilateral to the central line, then the contralateral arm, and finally the central line. • Digital dynamic images are obtained in a 64 × 64 matrix at 1 frame per second for 120 seconds. At the completion of the study, the central line is flushed with 5 mL of heparin lock flush solution. • Data are reviewed in a cine format as well as 1 second per frame digital images.
Clinical Presentation
Technique