Clinical Presentation
A 67-year-old woman with breast cancer and severe bone pain from multiple bony metastases. Figure A demonstrates the patient’s standard bone scan. The patient then received a palliative radionuclide therapy, and the scan in Figure B was obtained. What therapy did the patient receive?
Differential Diagnosis
• Samarium 153 (Quadramet): This is the only osseous therapeutic agent that can be adequately imaged (both β-and γ-emitter).
• Strontium 89 (Metastron): This is approved for therapy but cannot be imaged (pure β-emitter).
• Phosphate 32:
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