Clinical Presentation

A 57-year-old man presents with nausea, weight loss, and thrombocytopenia. Ignore the linear artifact in the dome of the liver.

(A) Coronal reformatted infused computed tomography (CT) shows splenomegaly with heterogeneous mottling and focal, hypodense lesions (arrow). The arrowheads indicate enlarged iliac chain lymph nodes. (B) Ultrasound shows round, hypoechoic lesions (arrows) in the spleen and coarse echotexture.

Differential Diagnosis

• Lymphoma: