268

FIGURE 268-1

FIGURE 268-2

FINDINGS Figure 268-1. This is an abnormal ¹²³I-FP-CIT (DAT scan) SPECT. There is symmetrical decrease of tracer uptake in the bilateral putamen indicating loss of dopamine transporters (DATs) compatible with the diagnosis of Parkinson disease (PD). Figure 268-2. Axial T2 MRI through the basal ganglia. There are no structural abnormalities in the bilateral basal ganglia.

DIFFERENTIAL DIAGNOSIS Normal pressure hydrocephalus (NPH), Parkinson-plus syndromes (progressive supranuclear palsy, multisystem atrophy, corticobasal degeneration), dementia with Lewy bodies, Alzheimer disease.

DIAGNOSIS PD with early cognitive impairment.

DISCUSSION

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