CASE 54
History: Three asymptomatic patients present in the second trimester for fetal ultrasound imaging.
1. What should be included in the differential diagnosis for the lemon sign seen in Figure A? (Choose all that apply.)
B. Chiari II malformation and myelomeningocele
D. Agenesis of the corpus callosum
2. What entity is most commonly associated with a strawberry-shaped skull?
A. Trisomy 21
B. Trisomy 13
C. Trisomy 18
3. Which syndrome is associated with a cloverleaf skull (Figure B)?
B. Trisomy 13
C. Trisomy 21
4. What is Spalding sign (Figure C)?
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