CASE 72
History: Two asymptomatic patients present with late first-trimester pregnancies.
1. Which of the following syndromes are associated with nuchal translucency? (Choose all that apply.)
B. Trisomy 13
C. Trisomy 18
2. What is the normal nuchal translucency for weeks 10 to 14 of gestation?
A. >6 mm
B. >10 mm
C. >7.5 mm
D. >3 mm
3. A combination of nuchal translucency, serum markers beta–human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein A, and advanced maternal age results in what sensitivity for Down syndrome?
A. 50% to 60%
B. 20% to 30%
C. 10% to 15%
D. 80% to 90%
4. What is the progression of a thickened nuchal translucency seen at 14 weeks?
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