Clinical Presentation
A 2-year-old girl presenting with developmental delay and seizures.
Imaging Findings
(A) Axial T1-weighted image (WI) shows severely decreased sulcation of the brain with a thick cortex (arrows). (B) Sagittal T1WI shows a thick cortical layer with severely decreased sulcation. (C) Axial T2WI shows severely decreased sulcation of the brain with a thick cortex (arrows). (D) Axial T2WI shows severely decreased sulcation of the brain with a thick cortex (arrows).
Differential Diagnosis
• Type I (classic) lissencephaly:
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