CASE 92
History: Two coronal images are presented of second-trimester fetal heads as incidental findings on routine ultrasound scans (Figures A and B).
1. What should be included in the differential diagnosis? (Choose all that apply.)
2. Does the alpha-fetoprotein (AFP) level help make this diagnosis?
D. No, it is too variable to be helpful.
3. What is Meckel-Gruber syndrome?
B. Macrocephaly
C. Microcephaly with a frontal meningoencephalocele