Questions

Answers

1. True or false: Non-Hodgkin lymphomas (NHLs) are a complex and heterogeneous set of many diseases.

1. true

2. True or false: The most common type of low-grade lymphoma is called B-cell small-cell lymphocytic.

2. false

3. True or false: NHLs are clinically divided into low-grade and high-grade, according to their natural history and survival.

3. true

4. True or false: Because low-grade NHLs are generally incurable, new treatments such as radioimmuno-therapy (RIT) are being sought.

4. true

5. True or false: In a stage III NHL, there is involvement of lymph node regions on both sides of the diaphragm.

5. true

6. True or false: Diagnostic computed tomography (CT) provides incremental value as compared with positron emission tomography/computed tomography (PET/CT) in the evaluation of lymphoma.

6. false

7. True or false: The accurate staging of Hodgkin lymphoma is important for guiding the choice of therapy and provides critical prognostic information.

7. true

8. Follicular lymphomas constitute what percentage of all NHLs?

8. C, 20% to 25%

9. Which of the following forms of nuclear imaging is useful or experimental in lymphoma?

A. ¹⁸F-FDG

B. ⁶⁷Ga (limited by spatial resolution, intestinal activity, low-grade tumors, and delayed scan time periods)

C. ⁶⁸Ga, ⁶⁶Ga

D. ¹⁸F-FLT

E. all of the above

9. E, all of the above

10. True or false: PET is as accurate as CT for staging patients with Hodgkin disease (HD).

10. false

11. When compared with CT, fluorodeoxyglucose (FDG) PET upstages patients with HD in what percentage of patients?

A. 5% to 10%

B. 10% to 20%

C. 20% to 25%

D. 30% to 40%

E. 50%

11. B, 10% to 20%

12. FDG PET changes the management of patients with HD after conventional work-up in what percentage of cases?

A. 5% to 10%

B. 10% to 20%

C. 20% to 25%

D. 30% to 40%

E. 50%

12. B, 10% to 20%

13. Which lymphomas have intense FDG uptake?

13. Hodgkin, diffuse large B-cell, mantle cell, and follicular lymphomas

14. Which lymphomas have low or moderate FDG uptake?

14. small lymphocytic, marginal zone B-cell, MALT, peripheral T-cell lymphomas

15. True or false: FDG PET has excellent sensitivity (greater than 90%) for the diagnosis and staging of patients with B-cell small-cell lymphocytic lymphoma.

15. false

16. True or false: FDG PET has excellent sensitivity for the diagnosis and staging of patients with follicular lymphomas.

16. true

17. True or false: FDG PET has moderate sensitivity (70% to 80%) for the diagnosis and staging of patients with marginal zone lymphoma.

17. true