Mammogram Underestimates Tumor Size

31 Mammogram Underestimates Tumor Size


Case 31.1: Mammogram Underestimates Tumor Size


Case History

A 69-year-old woman presents for screening mammogram.


Physical Examination

• Bilateral breast: multiple lumps


Mammogram

Calcifications (Fig. 31.1)


• Type: pleomorphic/heterogeneous


• Distribution: grouped/clustered


image


Fig. 31.1 The right breast has a cluster of heterogeneous calcifications (circle) in the upper outer breast. These calcifications are associated with architectural distortion in the CC view. The left breast has multiple round and oval masses that have been stable for several years. (A) Right MLO mammogram. (B) Left MLO mammogram. (C) Right CC mammogram. (D) Left CC mammogram. (E) Right ML spot magnification mammogram.


Ultrasound

Frequency


• 12 MHz


Mass (Fig. 31.2)


• Margin: ill defined


• Echogenicity: hypoechoic


• Retrotumoral acoustic appearance: posterior shadowing distal to mass


• Shape: irregular


image


Fig. 31.2 Right radial breast sonogram. Two hypoechoic irregular masses are present. Mass 1 is in the upper outer quadrant, and mass 2 is next to the nipple.


Pathology

• Mixed ductal and lobular carcinoma


• Two separate foci of mixed ductal and lobular carcinoma


Management

• BI-RADS assessment category 5, highly suggestive of malignancy



Pearls and Pitfalls


• In this case, it was not clear if the architectural distortion was associated with the abnormal calcifications, as the distortion was visible in only one view. Furthermore, the architectural distortion appeared much larger than the area of the calcifications. Sonography may be helpful when there is a mammographic imaging discrepancy. In this case, the abnormal mammographic calcifications and architectural distortion correspond to multifocal disease.


Suggested Reading

Baker JA, Soo MS. The evolving role of sonography in evaluating solid breast masses. Semin Ultrasound CT MR 2000;21:286–296


Buchberger W, Niehoff A, Obrist P, DeKoekkoek-Doll P, Dünser M. Clinically and mammographically occult breast lesions: detection and classification with high-resolution sonography. Semin Ultrasound CT MR 2000;21:325–336


Case 31.2: Mammogram Underestimates Tumor Size


Case History

A 45-year-old woman presents with thickening in the right breast, which she thinks might be a pulled muscle.


Physical Examination

• Right breast: large, mildly tender firm area extending from the 9 o’clock to the 12 o’clock positions in the right breast


• Left breast: normal exam


Mammogram

Mass (Fig. 31.3)


• Margin: ill defined


• Shape: oval


• Density: isodense

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Dec 24, 2015 | Posted by in BREAST IMAGING | Comments Off on Mammogram Underestimates Tumor Size

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