KEY FACTS
Terminology
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Clot formation in renal vein
Imaging
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Unilateral > bilateral
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Kidney enlarged acutely in 75% cases
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Renal vein dilated acutely
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Possible inferior vena cava (IVC) thrombus extension
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Altered renalarteryspectral waveforms
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↑ systolic pulsatility (narrow, sharp systolic peaks)
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Persistent retrograde diastolic flow
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Pathology
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Nephrotic syndrome: Most common cause of renal vein thrombosis in adults
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Hypovolemia/renal hypoperfusion: Most common cause of renal vein thrombosis in children
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Risk in neonates is associated with fetal distress, perinatal asphyxia, diabetic mothers, and volume contraction
Clinical Issues
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Outcome depends on cause, time to diagnosis, duration of occlusion, recanalization, collateralization
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Prognosis overall good; frequent spontaneous recovery
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Anticoagulation: Heparin then Coumadin or low-molecular-weight heparin for maintenance
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Thrombolysis/surgical thrombectomy: Heroic measure for life-threatening situations
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Suprarenal caval filter (IVC thrombus)
Scanning Tips
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Renal vein can be scanned from flank or epigastric window; flank window is more frequently used because it is less affected by body habitus and has fewer surrounding vessels
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Do not mistake splenic vein for left renal vein (when using epigastric window)
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Splenic vein anterior to superior mesenteric artery
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Left renal vein posterior to superior mesenteric artery
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