Infiltrative neoplasm of testis in which tumor cells surround and compress seminiferous tubules and normal testicular vessels

Bilateral, solid, hypoechoic, hypervascular nodules/masses

Diffuse hypoechoic testis with hypervascularity

Striated pattern

Testicular shape not altered

Normal testicular vessels with straight course crossing through lesions

Most commonly secondary lymphomatous involvement of testis; rarely primary

Lymphoma behaves similar to leukemia with abnormal cells diffusely infiltrating interstitium with compression of seminiferous tubules without causing their destruction

Testis is “sanctuary organ”: Blood gonad barrier limits accumulation of chemotherapeutic agents

Stages IE and IIE: Orchidectomy

Stages IIIE and IVE: Systemic chemotherapy using cyclophosphamide, doxorubicin, vincristine, and prednisolone

Radiation in symptomatic and bulky deposits

Lymphoma accounts for ~ 5% of all testicular tumors

Most common bilateral testicular tumor

Side-by-side comparison of both testes in single image with both grayscale and color Doppler is essential to assess for symmetry in size, echogenicity, and vascularity

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  Do not use dual image/split screen because scan parameters, such as TGC or color Doppler scale, may be altered between windows