Thyroid Cancer

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Thyroid Cancer










































Questions


Answers


1. True or false: Because well-differentiated thyroid cancer (WDTC) has a favorable natural history, prospective randomized studies using large numbers of patients are needed to demonstrate any therapeutic effect for universal radioiodine ablation (RAI).


1. true


2. True or false: In an analysis of data combined from multiple retrospective studies, the relapse rate after RAI was reduced by 10% among patients whose primary tumors were at least 1.0 to 1.5 cm in diameter, that were multicentric, or that had soft tissue invasion at diagnosis.


2. false


3. True or false: The image quality and diagnostic accuracy of 131I whole-body scans obtained after thyroid-stimulating hormone (recombinant human [rh]TSH) are equivalent to those obtained after thyroid hormone withdrawal (THW).


3. true


4. True or false: Thyroid hormone withdrawal or thyrogen stimulation prior to 18F-FDG might be useful, and its exact role is currently being evaluated.


4. true


5. What is the current status of Medicare and Medicaid coverage for 18FFDG PET in thyroid cancer?


A. covered for initial treatment strategy


B. covered for subsequent treatment strategy of follicular thyroid cancer


C. covered only with entry in NOPR for subsequent treatment strategy of thyroid cancers other than follicular type


D. covered for evaluation of cases with elevated serum Tg with a negative whole body 131I


E. all of the above


5. E, all of the above


6. True or false: Increased FDG uptake is seen in anaplastic, medullary, and hurtle cell thyroid carcinomas.


6. true


7. What are the FDA-approved indications for the use of rhTSH?


7. The use of rhTSH is approved for serum thyroglobulin (Tg) testing with or without radioiodine imaging in the follow-up of patients with well-differentiated thyroid cancer, and for radioiodine ablation of thyroid tissue remnants in patients who have undergone a near-total or total thyroidectomy for well-differentiated thyroid cancer and who do not have evidence of metastatic thyroid cancer.


8. True or false: Thyroglobulin (Tg) is secreted by normal and neoplastic thyroid cells and is currently measured by radioimmunoassay.


8. false


9. True or false: The greatest limitation in interpreting Tg levels is the potential for interference by anti-Tg autoantibodies.


9. true


10. Anti-Tg antibodies are found in what percentage of patients with WDTC?


A. 5% to 10%


B. 10% to 20%


C. 20% to 30%


D. 30% to 40%


E. 40% to 50%


10. C, 20% to 30%


11.

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Jan 24, 2016 | Posted by in NUCLEAR MEDICINE | Comments Off on Thyroid Cancer

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