Transplant Renal Artery Thrombosis





KEY FACTS


Terminology





  • Occlusion of transplant renal artery secondary to thrombus



Imaging





  • Edematous hypoechoic kidney if total thrombosis



  • Absence of blood flow in main renal artery



  • Diffuse absence of parenchymal perfusion on color or power Doppler



  • Blunted low-resistance waveforms in ischemic areas from collateral flow



  • If involving accessory renal artery




    • Segmental wedge-shaped peripheral area of decreased color flow and altered echogenicity




  • Color, power, spectral Doppler US 1st-line imaging modality for complications of renal transplantation



  • Optimize color and spectral Doppler settings for slow flow



Top Differential Diagnoses





  • Transplant renal vein thrombosis



  • Acute rejection/acute on chronic rejection



  • Hyperacute rejection



Clinical Issues





  • Rare (< 1%)



  • Abrupt onset of oliguria, decreased function, pain and swelling of allograft



  • Poor prognosis; graft loss typical when single main artery thrombosed




    • Transplant nephrectomy



    • Thrombectomy or thrombolysis rarely successful unless diagnosis made early




  • Accessory or segmental arterial thrombosis → ischemia and subsequent atrophy



Diagnostic Checklist





  • Severe acute rejection or tubular necrosis may cause propagating small vessel thrombosis resulting in infarction and mimicking transplant renal artery thrombosis



  • Urgent finding requiring prompt communication




Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Transplant Renal Artery Thrombosis

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