CASE 66 History: A 35-year-old man presents with left lower back and buttock pain for the past 6 months. The pain is worse at night; oral medications provide minimal relief. 1. What should be included in the differential diagnosis? (Choose all that apply.) b. Lymphoma d. Metastasis e. Chordoma 2. What percentage of spinal osteoblastomas are found in the sacrum? a. 3% b. About 20% d. 75% 3. What is the “flare phenomenon”? a. Redness in the skin overlying the tumor b. Rapid tumor growth after radiation therapy c. Peritumoral edema in bone and soft tissue d. Facial flushing seen in patients with osteoblastoma
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