• The breast lies on the chest wall and on the deep pectoral fascia • High spatial resolution is required to detect microcalcification: a short exposure time limits any movement artefact • There is a narrow range of inherent breast densities (as it is predominantly fatty tissue): low molybdenum energy peaks (17.5 and 19.6keV) provide high contrast (filtering reduces extraneous radiation) • Breast compression: this reduces geometric and movement unsharpness • Mediolateral oblique (MLO) view (standard): • Craniocaudal (CC) view (standard): • Paddle views (supplementary): • True lateral view (supplementary): • Magnification views (supplementary): • Eklund technique (supplementary): • Exaggeration of the normal cyclical proliferation and involution of breast tissue with the development of fibrosis • A benign tumour arising from the TDLU (fibrous stroma + epithelial ductal structures) • Requires biopsy for diagnosis unless <25 years old (to exclude malignancy) • Juvenile fibroadenoma: a more cellular variant occurring at a younger age • Phyllodes tumour: a fibroepithelial tumour similar to a giant fibroadenoma, affecting an older age group
Breast
NORMAL ANATOMY
the superficial pectoral fascia envelops the breast
suspensory ligaments (Cooper’s ligaments) connect the two layers
2 components
Collecting ducts open onto the tip of the nipple
Sebaceous glands within the nipple–areolar complex are called Montgomery’s glands
ducts open onto the skin surface (and are seen as small raised nodular structures called Morgagni’s tubercles)
This is divided into 15–25 lobes, each consisting of a branching duct system leading from the collecting ducts to the terminal duct lobular units (TDLUs)
Each duct drains a lobe made up of 20–40 lobules
Young women usually have dense glandular breast tissue
this is usually replaced by fatty tissues in older women with loss of the lobular units
Lymphatic drainage is usually to the axillary and internal mammary nodes
METHODS OF IMAGING
Imaging in mammography
it requires a very small focal spot (0.1–0.3mm)
grids are used to reduce scatter and increase contrast
digital mammography is now used
it improves contrast (it reduces scatter)
it reduces radiation dose (less tissue needs to be penetrated)
it achieves uniform image density
it separates superimposed breast tissues
it highlights rigid tumours (glandular tissue is compressible)
Mammography (digital/analogue) (MMG)
Evaluation of breast symptoms and signs, including masses, skin thickening, deformity, nipple retraction, nipple discharge and nipple eczema
Follow-up of breast cancer patients
Guidance for biopsy or localization of lesions not visible on ultrasound
The XR beam is directed from superomedial to inferolateral (usually at 30–60°)
compression is applied obliquely across the chest wall and perpendicular to the long-axis pectoralis major
The only view demonstrating the entire breast tissue on a single image
Well positioned if: the inframammary angle is demonstrated
the nipple is in profile
the nipple is positioned at the level of the lower border of the pectoralis major, with the muscle across the posterior border of the film at 25–30° to the vertical
The XR beam travels from superior to inferior
the breast is pulled forward and away from the chest wall with compression applied from above
Well positioned if: the nipple is in profile
it demonstrates virtually all of the medial tissue and the majority of the lateral tissue (with exclusion of the axillary tail of the breast)
the depth of breast tissue should be < 1cm of the distance from the nipple to the pectoralis major on the MLO projection
Localized compression applied with a compression paddle
It distinguishes a real lesion from superimposition of normal tissues
it defines the margins of a mass
The mammography unit is turned through 90° and a mediolateral or lateromedial XR beam used
It distinguishes superimposition of normal structures from real lesions
it increases the accuracy of wire localizations of non-palpable lesions
Performed in the craniocaudal and lateral projections
These interrogate areas of microcalcification and can demonstrate ‘teacups’ with benign calcification
INTRODUCTION
FIBROCYSTIC CHANGE
DEFINITION
regression with pregnancy and menopause
increased risk for developing certain types of cancer (e.g. ductal carcinoma in situ (DCIS))
BENIGN MASS LESIONS
FIBROADENOMA
DEFINITION
it often enlarges during pregnancy and regresses after the menopause
it is the most common cause of a benign solid mass in the breast
RADIOLOGICAL FEATURES
US
< 25% are locally aggressive requiring clear surgical margins
large fibroadenomas or those rapidly increasing in size are excised to avoid missing a phyllodes tumour
Breast
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