General characteristics of bone tumours

General characteristics of bone tumours

GENERAL CHARACTERISTICS OF BONE TUMOURS

AGE AT PRESENTATION

• Metastases are the commonest malignant bone tumours in patients that are > 45 years of age (an atypical metastasis is more common in this age group than a classical primary malignant tumour)

Primary malignant bone tumours are rare before 5 years of age

1^st decade: these are commonly disseminated bone lesions of leukaemia and neuroblastoma

2^nd decade: it is usually an osteosarcoma or Ewing’s sarcoma

RATE OF GROWTH

Benign and low-grade malignant neoplasms

• These tend to remain within the intramedullary cavity (until late) there is slow erosion of the endosteal cortex (leading to endosteal scalloping) periosteal new bone formation can lead to bone expansion and a well-defined sclerotic rim

High-grade malignant tumours

• These commonly extend through the cortex at presentation with associated cortical destruction, a non-sclerotic rim and an adjacent extraosseous mass

Lodwick pattern I (geographical)

Benign and low-grade malignant neoplasms

• There is a narrow zone of transition (a few mm) the most actively growing lesions (e.g. a GCT) have a non-sclerotic margin the least aggressive lesions show a sclerotic rim of varying thickness

Lodwick pattern II (moth-eaten)

The next most aggressive pattern

• The zone of destruction is made up of multiple ill-defined coalescing lucent areas (2–5mm) and implies cortical involvement (purely medullary lesions are not visible)

Lodwick pattern III (permeative)

The most malignant pattern

Only gold members can continue reading. Log In or Register to continue

Stay updated, free articles. Join our Telegram channel

Tags: Grainger & Allisons Diagnostic Radiology Essentials Expert Consu

Feb 27, 2016 | Posted by admin in GENERAL RADIOLOGY | Comments Off

Full access? Get Clinical Tree

Get Clinical Tree app for offline access

Get Clinical Tree app for offline access