11 Imaging Basics: Contrast-to-Noise Ratio (CNR)

The contrast-to-noise ratio (CNR) is defined as the difference in signal contribution (signal intensity; SI) between different tissues, divided by the background noise (N). For example, the contrast between cerebrospinal fluid (CSF) and white matter (WM) is given by |(SI_CSF – SI_WM)|/N. Note that this measurement is specific to the tissues being compared.

Figure 11.1

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