Liver Transplant Hepatic Venous Stenosis/Thrombosis





KEY FACTS


Imaging





  • Hepatic venous stenosis




    • Color Doppler




      • May see focal turbulent flow at stenosis and stenotic jet




    • Spectral Doppler




      • Elevated velocity at site of stenosis or < 10 cm/s away from site of stenosis



      • Loss of normal triphasic waveform




        • Most commonly monophasic in appearance




      • May see secondary slow portal vein velocity




    • Angiography




      • Pressure gradient > 5 mm Hg across stenosis





  • Hepatic venous thrombosis




    • Direct visualization of thrombus in hepatic vein (HV) or lack of detectable flow with color, power, or spectral Doppler




Pathology





  • HV or inferior vena cava (IVC) stenosis results in outflow obstruction of liver



  • Immediate posttransplant period: Kinking of vessel



  • Delayed presentation: Intimal hyperplasia



Clinical Issues





  • HV stenosis occurs in < 1% of liver transplants, 2-10% of liver transplants when piggyback technique used



  • Right lobe liver graft from living donor has higher risk of developing venous congestion because of inadequate venous drainage



  • Clinical presentation: Lower extremity edema, Budd-Chiari syndrome, ascites



  • Treatment




    • Stenosis may be treated with balloon-expandable stents or angioplasty



    • Thrombosis may require surgery or retransplant




Scanning Tips





  • Color Doppler box should always include HV and its IVC confluence because stenoses often occur at the junction



  • Obtain HV spectral Doppler tracings within 3 cm of junction with IVC



  • If area of aliasing is identified, obtain spectral Doppler with angle correction through the region




Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Liver Transplant Hepatic Venous Stenosis/Thrombosis

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