KEY FACTS
Imaging
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Hepatic venous stenosis
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Color Doppler
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May see focal turbulent flow at stenosis and stenotic jet
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Spectral Doppler
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Elevated velocity at site of stenosis or < 10 cm/s away from site of stenosis
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Loss of normal triphasic waveform
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Most commonly monophasic in appearance
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May see secondary slow portal vein velocity
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Angiography
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Pressure gradient > 5 mm Hg across stenosis
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Hepatic venous thrombosis
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Direct visualization of thrombus in hepatic vein (HV) or lack of detectable flow with color, power, or spectral Doppler
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Pathology
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HV or inferior vena cava (IVC) stenosis results in outflow obstruction of liver
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Immediate posttransplant period: Kinking of vessel
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Delayed presentation: Intimal hyperplasia
Clinical Issues
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HV stenosis occurs in < 1% of liver transplants, 2-10% of liver transplants when piggyback technique used
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Right lobe liver graft from living donor has higher risk of developing venous congestion because of inadequate venous drainage
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Clinical presentation: Lower extremity edema, Budd-Chiari syndrome, ascites
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Treatment
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Stenosis may be treated with balloon-expandable stents or angioplasty
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Thrombosis may require surgery or retransplant
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Scanning Tips
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Color Doppler box should always include HV and its IVC confluence because stenoses often occur at the junction
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Obtain HV spectral Doppler tracings within 3 cm of junction with IVC
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If area of aliasing is identified, obtain spectral Doppler with angle correction through the region