Liver Transplant Hepatic Venous Stenosis/Thrombosis





KEY FACTS


Imaging




  • •

    Hepatic venous stenosis



    • ○

      Color Doppler



      • –

        May see focal turbulent flow at stenosis and stenotic jet



    • ○

      Spectral Doppler



      • –

        Elevated velocity at site of stenosis or < 10 cm/s away from site of stenosis


      • –

        Loss of normal triphasic waveform



        • □

          Most commonly monophasic in appearance



      • –

        May see secondary slow portal vein velocity



    • ○

      Angiography



      • –

        Pressure gradient > 5 mm Hg across stenosis




  • •

    Hepatic venous thrombosis



    • ○

      Direct visualization of thrombus in hepatic vein (HV) or lack of detectable flow with color, power, or spectral Doppler




Pathology




  • •

    HV or inferior vena cava (IVC) stenosis results in outflow obstruction of liver


  • •

    Immediate posttransplant period: Kinking of vessel


  • •

    Delayed presentation: Intimal hyperplasia



Clinical Issues




  • •

    HV stenosis occurs in < 1% of liver transplants, 2-10% of liver transplants when piggyback technique used


  • •

    Right lobe liver graft from living donor has higher risk of developing venous congestion because of inadequate venous drainage


  • •

    Clinical presentation: Lower extremity edema, Budd-Chiari syndrome, ascites


  • •

    Treatment



    • ○

      Stenosis may be treated with balloon-expandable stents or angioplasty


    • ○

      Thrombosis may require surgery or retransplant




Scanning Tips




  • •

    Color Doppler box should always include HV and its IVC confluence because stenoses often occur at the junction


  • •

    Obtain HV spectral Doppler tracings within 3 cm of junction with IVC


  • •

    If area of aliasing is identified, obtain spectral Doppler with angle correction through the region




Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Liver Transplant Hepatic Venous Stenosis/Thrombosis

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