KEY FACTS
Terminology
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Obstructed renal collecting system containing pus or infected urine
Imaging
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Presence of mobile debris and layering of low-amplitude echoes within dilated collecting system on US
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Dilated collecting system containing intermediate- or high-density material on CT
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Enlarged kidney with perinephric inflammatory changes on CT
Top Differential Diagnoses
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Sterile hydronephrosis
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Complex renal cyst
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Urothelial carcinoma
Pathology
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Stagnant urine becomes infected, filled with white blood cells, bacteria, debris, and pus
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Chronic > acute ureteral obstruction
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Etiology
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Young adult: Calculus or ureteropelvic junction obstruction or duplicated collecting system more common
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Elderly: Malignant ureteral stricture other mechanical obstruction
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Clinical Issues
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Urologic emergency: Delay in diagnosis and treatment leads to irreversible renal parenchymal damage and renal failure
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Progress to bacteremia or septic shock and can lead to 25-50% mortality
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Symptoms include fever, chills, flank pain
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Most common organism: Escherichia Coli
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Treatment: Percutaneous nephrostomy
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Diabetes is risk factor for worse clinical outcomes
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Early diagnosis and drainage are crucial to prevent bacteremia and septic shock
Scanning Tips
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Coronal plane best demonstrates collecting system, renal contour, renal cortex, medulla, and renal vessels
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To obtain good coronal view, place probe between iliac crest and lower costal margin; start with midaxillary window then try posterior axillary line where rib spaces are wider
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Graded probe pressure may help move bowel gas away
in this case of pyonephrosis in an adult patient with multiple sclerosis on grayscale US imaging.
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