Pyonephrosis





KEY FACTS


Terminology





  • Obstructed renal collecting system containing pus or infected urine



Imaging





  • Presence of mobile debris and layering of low-amplitude echoes within dilated collecting system on US



  • Dilated collecting system containing intermediate- or high-density material on CT



  • Enlarged kidney with perinephric inflammatory changes on CT



Top Differential Diagnoses





  • Sterile hydronephrosis



  • Complex renal cyst



  • Urothelial carcinoma



Pathology





  • Stagnant urine becomes infected, filled with white blood cells, bacteria, debris, and pus



  • Chronic > acute ureteral obstruction



  • Etiology




    • Young adult: Calculus or ureteropelvic junction obstruction or duplicated collecting system more common



    • Elderly: Malignant ureteral stricture other mechanical obstruction




Clinical Issues





  • Urologic emergency: Delay in diagnosis and treatment leads to irreversible renal parenchymal damage and renal failure




    • Progress to bacteremia or septic shock and can lead to 25-50% mortality




  • Symptoms include fever, chills, flank pain



  • Most common organism: Escherichia Coli



  • Treatment: Percutaneous nephrostomy



  • Diabetes is risk factor for worse clinical outcomes



  • Early diagnosis and drainage are crucial to prevent bacteremia and septic shock



Scanning Tips





  • Coronal plane best demonstrates collecting system, renal contour, renal cortex, medulla, and renal vessels



  • To obtain good coronal view, place probe between iliac crest and lower costal margin; start with midaxillary window then try posterior axillary line where rib spaces are wider



  • Graded probe pressure may help move bowel gas away







Debris layers dependently in a mass-like fashion in this case of pyonephrosis in an adult patient with multiple sclerosis on grayscale US imaging.

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Nov 10, 2024 | Posted by in ULTRASONOGRAPHY | Comments Off on Pyonephrosis

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