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Radionuclides and Radiopharmaceuticals
Questions | Answers |
1. Nuclides with the same atomic number (i.e., the same number of protons) but different numbers of neutrons (e.g., 15O, 16O, 18O) are called __________. | 1. isotopes |
2. Two nuclides with the same atomic mass but different atomic numbers are called __________. | 2. isobars |
3. Two nuclides with the same number of neutrons but different atomic numbers are called __________. | 3. isotones |
4. What is a radionuclide? | 4. a nuclide that emits particulate or photon energy to achieve a more stable energy state |
5. Another name for a helium ion containing two protons and two neutrons is _________. | 5. an alpha (α) particle |
6. What is a beta (β) particle? | 6. an electron |
7. Why are alpha (α) and beta (β) particles not used for imaging? | 7. They do not exit the body efficiently and thus are not detected. |
8. What ratio of protons to neutrons favors beta (β) decay? | 8. a low proton-to-neutron ratio, as compared with stable nuclei |
9. What two particles are emitted from the nucleus during beta (β) decay? | 9. a beta (β) particle (electron) and an antineutrino |
10. What is the relationship between the mean energy and the maximum energy of a beta (β) spectrum? | 10. The mean energy is approximately one-third of the maximum energy. |
11. What ratio of protons to neutrons favors positron decay? | 11. a high proton-to-neutron ratio |
12. What particles are released from the nucleus during positron decay? | 12. a positron (antielectron) and a neutrino |
13. What is the minimum amount of nuclear energy required for positron decay? | 13. 1.02 MeV |
14. What is the fate of a positron? | 14. to travel a short distance, combine with an electron, and be annihilated |
15. When a positron is annihilated via combination with an electron, the result is the production of __________. | 15. two nearly opposed 511 keV photons |
16. What ratio of protons to neutrons favors electron capture decay? | 16. a high proton-to-neutron ratio |
17. What particle is released from the nucleus during electron capture decay? | 17. a neutrino |
18. What is released from the nucleus during isometric transition? | 18. gamma (γ) rays |
19. Other than wavelength, frequency, and energy intensity, the fundamental difference between X-rays and gamma (γ) rays is __________. | 19. that X-rays are produced from energy released due to changes in the quantum levels/values of orbital electrons of an atom, while gamma (γ) rays are produced from energy shifts in the nucleus |
20. When energy from a nuclear transition results in the emission of an orbital electron rather than a gamma (γ) ray, this process is called __________. | 20. internal conversion |
21. Internal conversion electrons increase the radiation dose to the patient because __________. | 21. Energy from the electron is absorbed within the patient’s body. |
22. When energy from an orbital transition results in the emission of an orbital electron rather than an X-ray, the electron is called __________. | 22. an Auger electron |
23. What does the term “metastable” mean? | 23. when an isomeric state is long-lived (i.e., longer than 10-12 seconds) |
24. After an electron is ejected from an inner shell orbital, what occurs? | 24. Outer shell electrons release energy by moving to now unoccupied, less energetic inner orbitals; the energy released by this transition is characteristic of X-ray radiation. |
25. What are the two methods used to create synthetically radioactive materials? | 25. Radioactive materials are produced by bombarding a target material with either ions or with neutrons. |
26. A __________ is used to bombard elements with neutrons. | 26. nuclear reactor |
27. A __________ is used to bombard elements with protons. | 27. accelerator (linear or cyclotron) |
28. Name the five common cyclotron-produced radionuclides used in nuclear medicine. | 28. 111In, 123I, 67Ga, 18F, and 201Tl |
29. a radioisotope that does not contain any nonradioactive species | |
30. What does the term “activity” mean? | 30. the rate of disintegration of a radio-nuclide |
31. The unit of radioactivity equal to 3.7 × 1010 disintegrations per second is called __________. | 31. the curie (Ci) |
32. What is a becquerel (Bq)? | 32. The derived unit of radioactivity used by modern metric system, the SI (Système International d’unités), is called the becquerel. One becquerel is equal to one disintegration per second, or 2.7027×10-11 Ci. |