68 Normal

CASE 68


Clinical Presentation


A 35-year-old woman is referred for PET with 2-deoxy-2-[18F-FDG].


image


Fig.68.1 PET scan with 18F-FDG.


Technique


• The patient is instructed to avoid vigorous exercise for 24 hours prior to the scan, fast for at least 4 hours before the study, drink water during the fasting and uptake periods, and void prior to the scan


• A venous serum glucose sample is obtained prior to the injection of 18F-FDG (reference range is < 120 mg/dl for non-diabetic patients and < 200 mg/dl for diabetic patients), and the patient’s height and weight are recorded


• A 10–20 mCi dose of 18F-FDG is injected intravenously (in a dimly lit quiet room for brain PET scans), and the patient is asked to rest comfortably in a room that is kept warm


• Most PET scans are now acquired on a hybrid PET/CT scanner, and a low dose spiral CT is acquired for attenuation correction of the PET images and for anatomic localization. Some centers may choose to perform oral and/or intravenous contrast-enhanced diagnostic CT as part of the PET/CT examination


• Sixty minutes following the 18F-FDG injection, the spiral CT is performed using a weight-based algorithm from the skull base to the upper thighs (for most oncologic indications), or from the vertex to the feet, or centered over the brain depending on the tumor being evaluated


• A 2D or 3D PET acquisition (depending on the manufacturer) is then performed over the same region (s), and all PET images are corrected for attenuation, detector efficiency, scatter, decay, and random coincidences


• Consistency in 18F-FDG injected dose, scan acquisition time relative to the injection time, and acquisition and reconstruction protocols is important when performing serial scanning on the same patient


Image Interpretation


Anterior view from the three-dimensional maximum-intensity pixel (MIP) image (Fig. 68.1) demonstrates intense 18F-FDG uptake in the brain, heart, renal collecting systems, ureters, and bladder. There is more moderate uptake in the liver, spleen, colon, and various mucosal structures of the head and neck, as well as mild uptake in the thyroid, mediastinal blood pool, bone marrow, and skeletal muscles.


Differential Diagnosis


Normal 18F-FDG-PET scan.


Diagnosis and Clinical Follow-Up


Normal 18F-FDG-PET scan. Diagnosis final, no clinical follow-up.


Discussion


This case reflects the typical normal findings in an 18

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Jan 24, 2016 | Posted by in NUCLEAR MEDICINE | Comments Off on 68 Normal

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