96 Multiple Endocrine Neoplasia

CASE 96


Clinical Presentation


Two years ago, a 30-year-old gravida 1, para 0 woman presented with severely labile hypertension during pregnancy, which continued into the postpartum period. Now she presents with elevated calcium, parathyroid hormone, and calcitonin.


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Fig. 96.1


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Fig. 96.2


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Fig. 96.3


Technique


111In-Pentetreotide Scan (also see 99mTc-Sestamibi Scan)


• If possible, withhold nonradiolabeled octreotide before the scan; withhold 24 hours for short- acting octreotide and 3 to 4 weeks for long-acting formulations.


• The patient should be well hydrated to enhance renal clearance.


• If the patient has an insulinoma, a glucose infusion should be available to treat paradoxical hypoglycemia.


• 6 mCi (222 MBq)


• Slow intravenous injection over 1 minute


• Medium-energy collimator


• 172- and 247-keV photopeaks, 20% window


• Planar: anterior and posterior views from head to pelvis at 4 and 24 hours


• SPECT: abdomen and pelvis at 4 hours


• SPECT: chest, abdomen, and pelvis at 24 hours


• Additional images can be obtained at 48 hours if there is uncertainty whether abdominal activity represents pathologic or physiologic uptake.


Technique


99mTc-Sestamibi Scan


• None


• 30 mCi (1110 MBq)


• Intravenous injection


• Low-energy, high-resolution collimator


• 140-keV photopeak, 20% window

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Jan 24, 2016 | Posted by in NUCLEAR MEDICINE | Comments Off on 96 Multiple Endocrine Neoplasia

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