11 Chest Wall and Pleura Epidemiology Most common thoracic deformity. Etiology, pathophysiology, pathogenesis Developmental anomaly, usually clinically silent Often associated with mitral valve prolapse. Modality of choice Radiographs, CT. Radiographic findings Right paramediastinal opacity with slight leftward shift of the heart shadow so that the right margin of the heart is no longer concurrent with the right margin of the mediastinum On the lateral film, the sternum appears significantly posterior to the anterior contour of the ribs The retrocardiac space is significantly narrowed. CT findings The axial image shows marked indentation of the sternum with loss of the normal convexity of the anterior chest wall, which instead appears concave. Pathognomonic findings See the radiographic and CT findings. Typical presentation Usually an asymptomatic incidental finding. Therapeutic options Surgical correction is indicated where the ratio between the transverse and sagittal thoracic axes (“pectus index”) is greater than 3.25. What does the clinician want to know? Severity and whether surgery is indicated.
Pectus Excavatum
Definition
Imaging Signs
Clinical Aspects
Differential Diagnosis
Middle-lobe atelectasis | – Normal sternum |
Middle-lobe pneumonia | – Clinical aspects – Normal sternum |
Tips and Pitfalls
Can be misinterpreted as middle lobe pathology.
Selected Reference
Goretsky MJ et al. Chest wall abnormalities: pectus excavatum and pectus carinatum. Adolec Med Clin 2004; 15: 455–471
Pneumothorax
Definition
Air in the pleural space.
Epidemiology
Most often a sequela of trauma or biopsy Spontaneous pneumothorax has an annual incidence of 10: 10 000.
Etiology, pathophysiology, pathogenesis
Primary: Spontaneous pneumothorax Often associated with apical bullae and hereditary connective tissue disorders (Marfan syndrome, Ehlers–Danlos syndrome).
Secondary: Traumatic Iatrogenic Emphysema Sarcoidosis Cystic lung disease (lymphangioleiomyomatosis, Langerhans cell histiocytosis) Parainfectious or postinfectious (Pneumocystis jirovecii pneumonia, staphylococcal pneumonia) Neoplastic (metastases of osteosarcoma).
Imaging Signs
Modality of choice
Plain chest radiograph (expiration film is not required).
Radiographic findings
Pleural line parallel to the chest wall with a space free of pulmonary parenchyma lateral to the lung itself Note: Typical signs can be absent in chest radiographs obtained in the supine patient Signs of anterior pneumothorax include a deep sulcus, unusually sharp diaphragmatic, cardiac, and mediastinal contours and increased transradiancy in the upper abdomen Tension pneumothorax is characterized by mediastinal shift and a flattened, caudally shifted diaphragmatic dome.
CT findings
Directly visualizes the air-filled pleural space Even anterior pneumothorax is readily demonstrated.
Pathognomonic findings
Pleural line with a space free of pulmonary parenchyma.
Clinical Aspects
Typical presentation
Sudden chest pain (90% of cases) and dyspnea (80%).
Therapeutic options
Drainage Bullectomy or pleurodesis may be indicated to treat recurrent pneumothorax Tension pneumothorax and recurrent pneumothorax require treatment Treatment is advisable in pneumothorax exceeding 25% of the volume of the hemithorax or about 500 mL.
Course and prognosis
Usually good.
What does the clinician want to know?
Demonstrate lesion Extent.
Differential Diagnosis
Bullous emphysema | – CT is recommended to differentiate this from encapsulated pneumothorax |
Artifact, skin or drape fold | – Mach effect (either stopping short of or entering the pleural space) that mimics a pleural line |
Tips and Pitfalls
False-negative or–positive findings.
Selected Reference
Seow A et al. Comparison of upright inspiratory and expiratory chest radiographs for detecting pneumothoraces. AJR Am J Roentgenol 1997; 166: 313
Wintermark M, Duvoisin B, Schnyder P. Trauma of the pleura. In: Schnyder P, Wintermark M (eds.). Radiology of blunt trauma of the chest. Berlin, Heidelberg, New York: Springer; 2000: 57–70
Pleural Effusion
Definition
Epidemiology
Common causes include increased hydrostatic pressure (heart failure), reduced plasma osmotic pressure (in cirrhosis of the liver, nephrotic syndrome, renal insufficiency), infection, pneumonia Less common causes include tumors, transdiaphragmatic passage of ascites, and collagen diseases.
Etiology, pathophysiology, pathogenesis
Transudate: Increased hydrostatic capillary pressure or reduced plasma osmotic pressure, protein concentration of 1.5–2.5g/dL Exudate: Increased capillary permeability (inflammatory or neoplastic), protein concentration > 3g/dL, lactate dehydrogenase > 200 IU, protein concentration ratio of pleural fluid to serum > 0.5, lactate dehydrogenase in pleural fluid ≥ 2/3 of serum lactate dehydrogenase.
Imaging Signs
Modality of choice
Ultrasound, plain chest radiographs.
Ultrasound findings
Anechoic or hypoechoic band posterior to the chest wall demarcated by hyper-echoic visceral pleura, which contrasts against the lung Echo inhomogeneities, septa, and pleural thickening suggest an exudate.
Radiographic findings
Findings depend on the extent of the effusion and patient position (erect or supine) With increased volume of effusion there is rounding of the costophrenic angles Lateralization of the diaphragmatic dome in subpulmonary effusion, distance between the gastric air bubble and base of the lung > 1.5 cm Obliteration of the diaphragmatic contour and loss of retrodiaphragmatic vascularity Basal shadow with meniscus sign Hemithorax shadow with mediastinal shift With the patient supine: Reduced transparency of the hemithorax and apical cap.
CT findings
Effusion initially accumulates in the posterior pleural recess Several signs distinguish pleural effusion from abdominal fluid—diaphragm sign (pleural fluid lies outside the diaphragmatic contour) Interface sign (fluid is sharply demarcated from liver or spleen in ascites) Displaced crus sign (pleural effusion displaces the diaphragmatic crus cranially and anteriorly) Bare area sign (ascites separates the liver from the diaphragm only as far as the coronary ligaments).
Pathognomonic findings
See “Radiographic findings.”
Clinical Aspects
Typical presentation
Dyspnea depending on the volume of effusion and the underlying disorder.
Therapeutic options
Depend on the underlying disorder.
Course and prognosis
Depend on the underlying disorder.
What does the clinician want to know?
Etiology Drainage of encapsulated fluid accumulations.
Differential Diagnosis
Malignant pleural effusion | – Often massive – Unilateral – Nodular pleural thickening in pleural metastases – Positive cytology |
Tuberculous pleural effusion | – Protein-rich (75g/dL) – High lymphocyte content (> 70%) – Positive culture in only 25% of cases |
Empyema | – Enhancement of visceral and parietal pleura – Split pleura sign |
Collagen diseases | – Especially systemic lupus erythematosus, Wegener granulomatosis, rheumatoid arthritis |
Chylothorax | – Density is 0 HU or less – Most common cause is trauma or lymphoma |