CHAPTER 20 Endoscopy of the upper and lower gastrointestinal tract
Introduction
‘Endoscopy’ simply refers to examining the inside of the body with a scope. Nowadays, we generally consider ‘endoscopy’ to be an examination of the gastrointestinal tract. Since the introduction of the flexible fiberoptic endoscopes in the 1960s, endoscopy has come a long way from the days of rigid sigmoidoscopy or rigid esophagoscopy. Modern endoscopes are used to carry out day-to-day diagnostic and therapeutic procedures of the gastrointestinal tract. For the purpose of this chapter, we will concentrate on flexible endoscopy.
Indications
Upper gastrointestinal tract (GI) endoscopy and lower gastrointestinal tract endoscopy means direct inspection of the esophagus, stomach, duodenum, small intestines and the colon using a flexible fiberoptic endoscope. A gastroscopy (aka esophago-gastroduodenoscopy or OGD) refers to the examination of the esophagus, stomach and duodenum, whereas enteroscopy refers to examination of the small intestines. Full examination of the colon to the cecum is known as colonoscopy, examination of just the left colon to the splenic flexure is known as flexible sigmoidoscopy.
Endoscopy and fluoroscopy can be used to investigate the GI tract, but there are advantages to endoscopy which may be taken into account when a clinician decides which test to request:
Types of endoscopy
Upper gastrointestinal endoscopy
Most upper GI endoscopy is carried out by a forward looking gastroscope. This investigation will allow examination to and in some cases into the proximal jejunum. To examine the small bowel, an enteroscope (essentially a very long gastroscope) or capsule endoscopy is used. In practice, patients would usually have undergone prior fluoroscopic investigation by means of barium follow-through or enteroclysis.
To prepare for upper gastrointestinal endoscopy patients are asked not to eat or drink for 4–6 hours prior to the procedure. The procedure can be done under local anesthetic to the throat or under sedation. The gastroscope is passed via the mouth, through the cricopharyngeal sphincter and into the esophagus. Once intubation is achieved the examination of the esophagus, stomach and duodenum is relatively straightforward (Figures 20.3, 20.4 and 20.5, see color insert). There are several blind spots that merit special attention. The view of the esophageal mucosa is often lost at the point of passage through the sphincter and lesions can be missed. If this is suspected, the patient should undergo a barium swallow or a rigid esophagoscopy. Another potential blind spot is the superior part of the gastric antrum and angulus. It is important to retroflex the gastroscope in the antrum to gain a good view of this area.
Small bowel endoscopy
Enteroscopy is used to examine mainly the proximal small bowel. This is a much more involved procedure than gastroscopy. Enteroscopy is indicated for diagnosis of small bowel diseases including obscure gastrointestinal bleeding, malabsorption, obtaining tissue biopsies following abnormal fluoroscopic studies as well as therapeutic procedures for treating small bowel bleeding or polyps.
Colorectal endoscopy
Visualization of the lower bowel can be performed using a rigid or flexible endoscope. Rigid sigmoidoscopy and proctoscopy usually occur in the outpatient clinic. The Association of Coloproctology of Great Britain and Ireland recommends that a patient referred for barium enema should have had at least a rigid sigmoidoscopy prior to referral (Guidelines for Management of Colorectal Cancer, 2007). The reason for this is that lesions very low down in the rectum may be missed on barium enema but seen on proctoscopy or rigid sigmoidoscopy. A rigid examination is especially important in patients presenting with bright red rectal bleeding as common pathologies such as distal proctitis or hemorrhoids may not be demonstrated on barium enema.
Flexible endoscopic examinations of the lower GI tract fall into two tests – flexible sigmoidoscopy and colonoscopy. Previously, there were separate endoscopes for each test but, in practice, a colonoscope is used for both. A colonoscope is a 160 cm long fiberoptic telescope that is inserted via the anus.

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