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Hyperdense Renal Lesions

Some renal lesions are hyperdense (greater in attenuation than normal renal parenchyma) on unenhanced images. Renal cell carcinomas are usually isoattenuating or hypoattenuating on unenhanced images. A minority (13% in one study)¹ are hyperattenuating. A rare cause of a hyperdense renal lesion is focal chronic tubulointerstitial inflammation. This is a nonspecific response to persistent tubular injury, which causes the tubules to become filled with concentrated proteinaceous fluid.²

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