Mastocytosis

 Peptic ulcer disease and malabsorption


image Duodenum and SB: Thick folds, fast transit

image Mucosal nodularity (2-3 mm sand-like nodules)
– Fluid-distended lumen of SB


• Hepatomegaly (40% of adult cases)

• Biliary tree: Infiltration of walls; irregular strictures

• Splenomegaly with nodular deposits (50% of cases)

• Lymphadenopathy; thickened omentum and mesentery

• Sclerotic &/or lytic lesions in axial skeleton

• Bone scan: Lytic lesions, osteoporosis or osteosclerosis




TOP DIFFERENTIAL DIAGNOSES




• Carcinoid tumor

• Zollinger-Ellison syndrome

• Celiac-sprue disease

• Malabsorption conditions

• Primary sclerosing cholangitis (for biliary involvement)


PATHOLOGY




• Systemic mastocytosis is one of the myeloproliferative neoplastic conditions
image Along with polycythemia, myelofibrosis, CML, etc.

Only gold members can continue reading. Log In or Register to continue

Related posts:

Peribiliary Cysts Cecal Volvulus Biloma Congenital Hepatic Fibrosis Choledochal Cyst Crohn Disease

Stay updated, free articles. Join our Telegram channel
Tags:
Nov 16, 2016 | Posted by in GASTROINTESTINAL IMAGING | Comments Off on Mastocytosis

Full access? Get Clinical Tree
Get Clinical Tree app for offline access