84 The appearance of the liver can mimic cirrhosis in several conditions. This has been referred to as pseudocirrhosis. Pseudocirrhosis can be seen after chemotherapy, in livers both with and without metastatic disease. In patients with metastatic disease to the liver treated with chemotherapy, the appearance of pseudocirrhosis can evolve over 1 to 3 months. Pathologically, nodular regenerative hyperplasia is usually seen (rather than scar formation at the site of treated metastases). The appearance of pseudocirrhosis may make imaging evaluation difficult, as these patients often have residual disease in the cirrhotic-appearing liver.1
Mimics of Cirrhosis