Aase-Smith syndrome

α ₁ -Antitrypsin syndrome

Anemia (e.g., thalassemia, sickle cell, pyruvate kinase deficiency)

Chédiak-Higashi syndrome

Cogan’s syndrome

Ethanolamniosis

Farber’s syndrome

Felty’s syndrome

Fetal infection (e.g., herpes simplex, rubella, cytomegalovirus infection)

Gaucher’s disease, types I and III

Gangliosidosis (e.g., GM ₁ , GM ₂ )

Hepatic fibrosis and renal cystic disease

Hyperlipoproteinemia

Lipoatrophic diabetes

Mucopolysaccharidosis

Niemann-Pick disease

Osteopetrosis

Rubella syndrome

Sea-blue histiocyte syndrome

Vaquez-Osler syndrome

Inflammatory bowel disease

Hereditary hypoplasia

After irradiation

Infarction

Polysplenia syndrome

Sickle cell anemia

Polycythemia

Sarcoidosis

Leukemia

Tuberculosis

Malaria

Brucellosis

Congestion from portal hypertension

Leukemia

Lymphoma

Multiple myeloma

Abscesses (e.g., pyogenic, fungal)

Metastases

Septic emboli

Infarction

Lymphoma

Cysts (e.g., simple, epidermoid, hydatid, pancreatic)

Lymphangiomatosis

Granulomatous disease (e.g., tuberculosis, Mycobacterium avium-intracellulare infection, sarcoidosis, cat-scratch disease)

Hamartoma, hemangioma

Splenic artery aneurysm

Disseminated Pneumocystis carinii ( Pneumocystis jiroveci ) infection

Hereditary spherocytosis

Infarct (chronic)

Hematoma

Metastases

Calcified granulomas

Plasmacytoma

Abscess with air bubbles

Schistosomiasis

Cholesterol crystals in simple cyst

Hydatid “sand” in hydatid cyst

Hematoma

Abscess

Infarct

Angiosarcoma

Hemangioma

Hemangiosarcoma