Ultrasound Imaging Assessment Following Endovascular Aortic Aneurysm Repair

28 Ultrasound Imaging Assessment Following Endovascular Aortic Aneurysm Repair

Frequent assessment and objective follow-up are critical following endovascular aneurysm repair. Endografts, sometimes referred to as endovascular grafts, stent-grafts or transluminally placed endovascular grafts, continue to evolve and change in their design. Patients undergoing endovascular abdominal aortic aneurysm (AAA) repair require routine, lifelong follow-up and imaging surveillance.

Color Doppler ultrasound has been used for aortic endovascular graft evaluation and has the advantage of being noninvasive, inexpensive, rapid, safe, nontoxic, easily repeatable, and well tolerated by patients. This technique has already become an important tool in both the planning and the postoperative evaluation of endovascular grafts placed for a variety of vascular lesions and complications.19 Color Doppler imaging combines many of the ideal features of both angiography and spiral computed tomography (CT). It allows the examiner to make both quantitative and qualitative assessments of blood flow through the endovascular graft, and via a combination of pulsed-wave and color flow Doppler, can easily demonstrate normal blood flow patterns or abnormal flow patterns associated with specific pathologies. Because color Doppler is relatively inexpensive, easily repeatable, and without known risks, it has become a primary means of surveillance for endovascular interventions.2,4,5,7,10

The primary objectives of the color Doppler examination following endovascular AAA repair are to:

It is important to determine the origin of any blood flow signals identified within the aneurysm sac (endoleak source, Table 28-1) because the source of the blood flow signals and their characteristics may determine subsequent treatment.

TABLE 28-1 Endoleak Types

Type 1a, 1b Endoleak whose origin is at the proximal (1a) or distal (1b) stent attachment site.
Type 2 Endoleak originating from a branch vessel. Possible sources include patent lumbar (posterior to the endovascular graft sonographically), inferior mesenteric (anterolateral to the endovascular graft sonographically), accessory renal or hypogastric arteries, or other patent branches of the abdominal aorta. These are best seen in the transverse orientation.
Type 3 Endoleak that originates at the junctions between components of modular devices or from fabric tears within the graft.
Type 4 Transgraft flow or flow that fills the aneurysm sac because of porosity of the graft.
Endotension Increase in aneurysm size in the absence of endoleak.

Cross-sectional diameter measurements are recorded at each visit to determine maximum aneurysm size. When an aneurysm sac is excluded from the circulation, an aneurysm should remain stable or decrease in size over time.10,11 Any increase in size suggests that there is preserved blood flow into the aneurysm sac (endoleak) and because of the associated increase in blood pressure, a continued risk for rupture.11,12 However, increases in size have been reported without CT, angiographic, or color Doppler evidence of endoleak (endotension) and proven by direct pressure measurements in the aneurysm sac.1315

It is also important to determine that the distal arterial circulation has been preserved by ensuring that there are no graft-threatening abnormalities within the body of the endovascular graft, the graft limb(s) or in the inflow and outflow arteries. We previously described a protocol for evaluation of endovascular grafts placed at the aortoiliac level.2

If abnormalities are detected by color Doppler imaging, contrast arteriography and spiral CT may then be used to further characterize the abnormality when an intervention is being considered. This chapter describes a protocol for assessing endovascular grafts performed for the repair of isolated aneurysms of the abdominal aorta as well as aortoiliac aneurysms.

Endovascular Grafts: Overview and General Considerations

The endoluminal placement of stent-grafts, at sites remote from where the graft is introduced, allows for repair of a variety of complex lesions while reducing the relatively high morbidity and mortality associated with traditional open operative repair. The first series of transluminally placed endovascular grafts for the repair of abdominal aortic aneurysms in high-risk patients was reported in 1991.16 Since that time, significant advances in the design of endovascular stents and grafts have facilitated their deployment in aortic and aortoiliac aneurysms, permitting a greater number of patients to be treated with these devices.1720 We have extensive experience with the Montefiore Endovascular Graft System (MEGS), which has now expanded to include a number of commercially available endografts (Figure 28-1).

Currently several devices (Table 28-2) have been granted U.S. Food and Drug Administration approval for the treatment of aortoiliac aneurysms and are available for widespread use in the United States. Many other devices are undergoing clinical trials in the United States and abroad.2123

TABLE 28-2 Food and Drug Administration–Approved Grafts for Endovascular Abdominal Aortic Aneurysm Repair

Endovascular grafts are a combination of intravascular metallic stents and prosthetic graft materials. The stent functions as the fixation component of the endovascular graft, anchoring it to normal portions of the aorta and iliac arteries in lieu of standard suture anastomotic techniques. Fixation of the graft can be based on the column strength of the device, the net radial force that pushes outward onto the neck of the aneurysm, or the suprarenal stent components. The stent can be made of nitinol, stainless steel, or a cobalt-chromium alloy. Gore-Tex (polytetrafluoroethylene [PTFE]) and Dacron are the fabrics most commonly used as the prosthetic graft material component of the endograft. Once the endovascular graft is fixed into position, blood should flow only through the endovascular graft, thereby excluding the aneurysm sac from the effects of blood pressure and blood flow. Endovascular grafts come in many types and configurations (Figure 28-2). It is not uncommon for endovascular aortic aneurysm repair to be supplemented by other ancillary procedures such as femorofemoral artery bypass, intra-arterial coil vessel occlusion, or other vessel occlusion procedures (Figure 28-3). Newer endovascular grafts can treat a variety of complex arterial pathologies, and their surveillance becomes more complex. Examples include grafts with hypogastric branches and endografts with incorporated proximal fenestrations and branches.

Since most aortic aneurysms are infrarenal, the proximal component of the endovascular graft is deployed immediately below the lowest renal artery and extends distally as close as possible to the common iliac bifurcation. The device has an uncovered metal component when there is need for suprarenal fixation. The uncovered part of the stent crosses the orifices of the renal arteries. This design is thought to provide better fixation of the graft to the surrounding arterial wall, thereby reducing the potential for proximal graft migration and providing for a better proximal seal (Figure 28-4).

While the endovascular repair of AAAs offers many benefits (Table 28-3), there are several potential complications specific to this technique. The most significant of these complications are endoleaks24,25 and graft migration. These two complications have been seen in all of the endovascular graft designs that have been used for endovascular AAA repair.

TABLE 28-3 Advantages of Endovascular Graft Exclusion of Abdominal Aortic Aneurysms

An endoleak is defined as blood flow outside of the endovascular graft into the aortic aneurysm sac. This leak pressurizes the aneurysm sac and leads to continued risk for aneurysm enlargement and rupture. The presence of an endoleak, therefore, negates the primary goal of the endovascular procedure and results in an aneurysm that remains inadequately treated.11,2430 Considerable progress in patient selection and surgical technique has reduced the overall rate of all types of complications seen after endovascular AAA repair (Table 28-4). Traditionally the optimal method for postendovascular graft screening and the most reliable method for detecting complications is a contrast CT scan. However, this method is invasive, expensive, and involves radiation exposure to the patient and risk for possible contrast nephrotoxicity. Color Doppler ultrasound has been increasingly and successfully used to follow patients after endograft placement. It can be used to identify patients who may require further intervention with or without the need for additional preprocedural imaging.31,32

TABLE 28-4 Complications Associated With Endovascular Repair of Abdominal Aortic Aneurysms

Aneurysm growth
Fabric tears
Graft infection
Graft migration*
Limb thrombosis
Limb separation
Stent and/or attachment site fracture

* Common to all endovascular grafts used to date.

Color Doppler Ultrasound Technique

We generally allocate 60 to 90 minutes and up to 2 hours per study depending on the complexity of the intervention and the patient’s body habitus. This allows enough time to prepare the patient and room, perform the imaging component of the examination, and provide a preliminary report for the interpreting physician after the scan is completed.

Technologist Preparation

Before ultrasound evaluation, the technologist/sonographer performs a brief history for symptoms of claudication (hip, buttock, or lower extremity) and impotence (as applicable), and a physical examination that includes palpation of the aortic and femoral pulses. An ankle-brachial index and/or pulse volume recording can be obtained bilaterally and compared to the preoperative measurement, where available, to ensure that baseline blood flow to the extremities has been maintained.

To perform a thorough and optimal examination of the endovascular graft, the examiner must have considerable knowledge of the endovascular technique and of the various endovascular graft designs and configurations that are available and must be familiar with the details of the surgical procedure.

To this end, a review of all previous imaging studies is mandatory. This includes any preoperative or postoperative CT scans, color Doppler scans, or angiograms, as well as any intraoperative imaging studies that have been performed. This review is important because the examiner must be familiar with the configuration and specific anatomy of the endovascular graft,17,33,34 including the locations of the proximal and distal attachment sites. This information is used to document endovascular graft migration (if it occurs) and to identify all possible endoleak sources in advance of the color Doppler examination (Figure 28-5). In addition, review of the operative report or discussion with the operating surgeon is recommended to determine if the following apply: (1) coil embolization of branch vessels or use of other vessel occlusion devices, (2) supplemental proximal or distal arterial reconstructive procedures, and (3) other vessels have been treated with stents, either within the endovascular graft to support a portion of the graft or in the native artery to treat occlusive disease. The sonographic examination includes not only the aortic/iliac stent graft but also all other related arterial occlusion/reconstruction procedures.

Mar 5, 2016 | Posted by in ULTRASONOGRAPHY | Comments Off on Ultrasound Imaging Assessment Following Endovascular Aortic Aneurysm Repair
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