Whipple Disease

 Distal duodenum and jejunum are most often involved, with distal small bowel/ileum involved in severe cases


image Thickened, irregular folds with sand-like micronodules

image Small bowel lumen may be normal or mildly dilated


• CT
image Low-density enlarged mesenteric and retroperitoneal lymph nodes that may have near fat-density

image Thickened proximal small bowel folds ± submucosal edema due to hypoalbuminemia

• MR
image Lymph nodes may show ↑ T1 signal due to fat




TOP DIFFERENTIAL DIAGNOSES




• Celiac disease

• Intestinal opportunistic infections

• Dysgammaglobulinemia

• Intestinal metastases and lymphoma

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Nov 16, 2016 | Posted by in GASTROINTESTINAL IMAGING | Comments Off on Whipple Disease

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