Mucosal plaques in immunocompromised patients
Predominantly mid or upper esophagus
Plaques: Several mm in size, usually < 1 cm
Longitudinally oriented plaques
90% sensitivity in detecting
Candida esophagitis
PATHOLOGY
•
Most common cause of infectious esophagitis
Only 50% of patients with
Candida esophagitis are found to have thrush
CLINICAL ISSUES
•
Odynophagia (sharp pain on swallowing)
•
Immunocompromised patients
Occurs in patients with AIDS, hematologic malignancies
•
Other patients with physiologic or mechanical obstruction of esophagus and local stasis (e.g., achalasia)
•
Usually self-limited with rapid response to oral therapy
DIAGNOSTIC CHECKLIST
•
Odynophagia with plaques in immunocompromised patient should suggest candidiasis
•
Plaques are raised mucosal lesions; if central contrast collection is present then lesion is ulcer
•
Oral thrush plus odynophagia is presumptive evidence of
Candida esophagitis
TERMINOLOGY
Synonyms
•
Esophageal candidiasis, moniliasis
Definitions
•
Infectious esophagitis caused by fungi of
Candida species, usually
Candida albicans
IMAGING
General Features
•
Best diagnostic clue
Mucosal plaques in immunocompromised patient
•
Location
Any part or entire esophagus