CASE 111 34-year-old man with recent sore throat, chills, and fever, subsequently developed hematuria, dysuria, cough, dyspnea, hemoptysis, and respiratory failure AP chest radiograph (Fig. 111.1A) reveals diffuse bilateral air space opacities. Chest CT (lung window), coronal reformatted image (Fig. 111.1B), and axial images (Figs. 111.1C, 111.1D) reveal diffuse bilateral ground glass opacity and patchy areas of consolidation. Diffuse Alveolar Hemorrhage; Goodpasture Syndrome Fig. 111.1 • Idiopathic Pulmonary Hemorrhage • Other Diffuse Pulmonary Hemorrhage Syndromes • Sequela of Drug Therapy • Crack Cocaine Abuse • Environmental Exposures • Bone Marrow and Heart-Lung Transplantation • Dieulafoy Disease (e.g., endobronchial vascular malformation)
Clinical Presentation
Radiologic Findings
Diagnosis
Differential Diagnosis
Wegener Granulomatosis
Henoch-Schonlein Purpura
Microscopic Polyangiitis Pauci–Immune Glomerulonephritis
Systemic Lupus Erythematosus
Drug-Induced Coagulopathy
Penicillamine; Nitrofurantoin; Amiodarone
Paraquat (Zeneca Ag Products, Wilmington, DE)
Pesticides
Leather Conditioners
Isocyanates
Discussion
Background
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