160 Non-Neoplastic Lymphadenopathy: Mediastinal Fibrosis

CASE 160

image Clinical Presentation

28-year-old woman with chest pain and dyspnea

image Radiologic Findings

PA chest radiograph (Fig. 160.1) demonstrates decreased right lung volume, right hilar fullness, and paucity of right lower lobe vasculature. Axial and coronal contrast-enhanced chest CT (mediastinal window) (Figs. 160.2, 160.3) shows a right hilar soft-tissue mass with multifocal internal calcifications that obliterates the lumen of the right pulmonary artery. Contrast-enhanced chest CT (lung window) (Fig. 160.4) reveals attenuation in the caliber of the right lower lobe pulmonary arteries and right lower lobe peripheral ground glass opacity.

image Diagnosis

Mediastinal Fibrosis

image Differential Diagnosis

• Lung Cancer

• Lymphoma

• Metastatic Mediastinal Lymphadenopathy

• Other Non-Neoplastic Lymphadenopathies

image Mycobacterial Infection

image Fungal Disease

image Sarcoidosis

image Silicosis


Fig. 160.1


Fig. 160.2

image Discussion


Mediastinal fibrosis is the proliferation of dense fibrous tissue in the mediastinum with resultant focal or infiltrative masses, which may be locally invasive.


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Jan 14, 2016 | Posted by in RESPIRATORY IMAGING | Comments Off on 160 Non-Neoplastic Lymphadenopathy: Mediastinal Fibrosis

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