42

Case 42



Indication: Screening mammography.


History: Unremarkable.


Risk profile: Normal.


Age: 54 years.


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Clinical Findings


No findings.


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Fig. 42.1 Ultrasound.


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Fig. 42.2a,b Digital mammography, CC view.


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Fig.42.3a,b Digital mammography, MLO view.


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Fig. 42.4 Spot compression, left breast.


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Fig. 42.5a-c Contrast-enhanced MRI of the breasts.


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Fig. 42.6a-c Contrast-enhanced MRI of the breasts.


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Fig. 42.7 Contrast-enhanced MR mammography. Maximum intensity projection.


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Fig. 42.8a-d Signal-to-time curves.











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Please characterize ultrasound, mammography, and MRI findings.


What is your preliminary diagnosis?


What are your next steps?


This case demonstrates the imaging studies of an asymptomatic woman presenting for screening.


Ultrasound


In the upper outer quadrant of the left breast there was an irregular, hypoechoic lesion with distal acoustic shadowing (diameter8 mm). US BI-RADS left 4.


MR Mammography


MRI demonstrated a spiculated, ill-defined mass (diameter: 1 cm) in the upper outer quadrant with strong initial signal increase and postinitial plateau as well as a reduced signal in T2-weighted imaging. 1.2 cm caudal of this mass there were two homogeneously enhancing lesions, each of 5 mm diameter, with initial signal increase of 80% and postinitial plateau as well as reduced signal in T2-weighted imaging (MRI BI-RADS 3).


Mammography


Imaging showed an asymmetric (right>left), partially inhomogeneous dense parenchyma, ACR type 3. There was an isodense, slightly spiculated mass (diameter 1 cm) in the upper outer quadrant of the left breast. Spot compression obtained a more precise depiction of the spiculated quality of this lesion. BI-RADS right 1/left 4. PGMI: CC view P; MLO view G (inframammary fold).


Note


The lesion in the upper outer quadrant of the left breast was visible, at a similar size, in MR images produced 3 years previously in another clinic (Fig. 42.9).


MRI Artifact Category: 2


MRI Density Type: 1


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Fig. 42.9 MR mammography three years earlier demonstrated a hypervascularized lesion in the left breast [imaging not performed by authors]. 256 matrix.


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Fig. 42.10 Current MR mammography for comparison. 512 matrix.


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image Preliminary Diagnosis


Left upper outer quadrant: Carcinoma.


Left between outer quadrants: Fibroadenoma.


image Differential Diagnosis


Adenosis, papilloma.


 































BI-RADS Categorization


Clinical Findings


right 1


left 1


Ultrasound


right 1


left 4


Mammography


right 1


left 4


MR Mammography


right 1


left 4


BI-RADS Total


right 1


left 4


 


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Fig. 42.11 a,b US-guided core biopsy of the left breast. Pre-fire and post-fire documentation.


Procedure


US-guided core biopsy and histopathological evaluation of the lesion in the upper outer quadrant of the left breast (Fig. 42.11a,b).


Histopathology of the core biopsy specimen


Tubular carcinoma.


Further procedure


Open biopsy of the tubular carcinoma as well as of the secondary lesions in the left breast after MRI-guided hook-wire localization(Fig. 42.12).


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Fig. 42.12a-c MR-guided preoperative hook-wire localization. Pre-contrast image, subtraction image and documentation of the wire inposition.


Sep 3, 2016 | Posted by in GENERAL RADIOLOGY | Comments Off on 42

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