1. Describe the composition and behavior of atomic nucleus.
2. Describe different types of radiation.
3. List possible methods for producing radionuclides.
4. Describe different approaches for radiolabeling with positron emission tomography (PET) radionuclides.
5. Identify the difference between radiochemicals and radiopharmaceuticals.
6. List commonly used tests for quality control of radiopharmaceuticals.
Table 2.1 CLASSIFICATION OF NUCLEI ON THE BASIS OF THE NUMBER OF NUCLEONS
Table 2.2 THE MASSES OF THE ATOMIC PARTICLES
on the energy, the gamma photons can interact with the orbital electrons, the nuclear field, and the nucleus.
curies per millimole (Ci/mmol) or microcuries per microgram (µCi/µg). The mass of a radionuclide in a given amount of activity can be determined from the number of radioactive atoms present. For small capacity and high affinity receptor binding, a high specific activity of radioligands is demanded, whereas a low specific activity of radiotracers may be acceptable for large capacity and low affinity biological systems.